Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus - Wikidata - awgldk - TriplyDB

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

http://www.wikidata.org/entity/Q36403653

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Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA Spatiotemporal Regulation of Hsp90-Ligand Complex Leads to Immune Activation Targeted therapeutics in SLE: emerging strategies to modulate the interferon pathway Neutrophil extracellular traps (Nets) impact upon autoimmune disorders Inflammatory cytokines in systemic lupus erythematosus Toll-like receptors in systemic lupus erythematosus: potential targets for therapeutic intervention Review of experimental animal models of biliary acute pancreatitis and recent advances in basic research The TLR and IL-1 signalling network at a glance The enemy within: endogenous retroelements and autoimmune disease Nucleic acids and endosomal pattern recognition: how to tell friend from foe?Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection Sequences derived from self-RNA containing certain natural modifications act as suppressors of RNA-mediated inflammatory immune responses Cell Type-Specific Recognition of Human Metapneumoviruses (HMPVs) by Retinoic Acid-Inducible Gene I (RIG-I) and TLR7 and Viral Interference of RIG-I Ligand Recognition by HMPV-B1 Phosphoprotein Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands Toll-like receptor 8 senses degradation products of single-stranded RNA Toll-like receptors in the pathogenesis of autoimmune diseases: recent and emerging translational developments Pathogenic Inflammation and Its Therapeutic Targeting in Systemic Lupus Erythematosus HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses TLR8 deficiency leads to autoimmunity in mice The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity Nucleic acid scavenging polymers inhibit extracellular DNA-mediated innate immune activation without inhibiting anti-viral responses Guanine-modified inhibitory oligonucleotides efficiently impair TLR7- and TLR9-mediated immune responses of human immune cells Cancer immunotherapy via dendritic cells Recent insights into the implications of metabolism in plasmacytoid dendritic cell innate functions: Potential ways to control these functions CD2 distinguishes two subsets of human plasmacytoid dendritic cells with distinct phenotype and functions.Functional interaction of plasmacytoid dendritic cells with multiple myeloma cells: a therapeutic target.Phagosomal signaling by Borrelia burgdorferi in human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-beta Antiviral defense: interferons and beyond Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion.Plasmacytoid dendritic cells, interferon signaling, and FcγR contribute to pathogenesis and therapeutic response in childhood immune thrombocytopenia.Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura Viraemia, immunogenicity, and survival outcomes of cytomegalovirus chimeric epitope vaccine supplemented with PF03512676 (CMVPepVax) in allogeneic haemopoietic stem-cell transplantation: randomised phase 1b trial Nanoparticle-delivered multimeric soluble CD40L DNA combined with Toll-Like Receptor agonists as a treatment for melanoma.Borrelia burgdorferi RNA induces type I and III interferons via Toll-like receptor 7 and contributes to production of NF-κB-dependent cytokines Immunotherapy of Dual-Function Vector with Both Immunostimulatory and B-Cell Lymphoma 2 (Bcl-2)-Silencing Effects on Gastric Carcinoma.Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1.Interferon-alpha: a therapeutic target in systemic lupus erythematosus Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation.A genomic approach to human autoimmune diseases.

P2860

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P2860

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

http://www.wikidata.org/entity/Q36403653

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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2005年學術文章

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name

Nucleic acids of mammalian ori ...... e systemic lupus erythematosus

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Nucleic acids of mammalian ori ...... e systemic lupus erythematosus

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type

label

Nucleic acids of mammalian ori ...... e systemic lupus erythematosus

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Nucleic acids of mammalian ori ...... e systemic lupus erythematosus

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prefLabel

Nucleic acids of mammalian ori ...... e systemic lupus erythematosus

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Nucleic acids of mammalian ori ...... e systemic lupus erythematosus

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P1433

Journal of Experimental Medicine

P1476

Nucleic acids of mammalian ori ...... e systemic lupus erythematosus

@en

P2093

Bonnie Chang

http://www.w3.org/2001/XMLSchema#string

Franck J Barrat

http://www.w3.org/2001/XMLSchema#string

Jean H Chan

http://www.w3.org/2001/XMLSchema#string

Josh Gregorio

http://www.w3.org/2001/XMLSchema#string

Omar Duramad

http://www.w3.org/2001/XMLSchema#string

Robert L Coffman

http://www.w3.org/2001/XMLSchema#string

Satoshi Uematsu

http://www.w3.org/2001/XMLSchema#string

Thea Meeker

http://www.w3.org/2001/XMLSchema#string

P2860

A Toll-like receptor recognizes bacterial DNA

Interleukin-10 and the interleukin-10 receptor

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

Toll-like receptor signalling

Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs

Systemic lupus erythematosus and the type I interferon system

Innate immune recognition

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus

IRF-7 is the master regulator of type-I interferon-dependent immune responses

P304

1131-1139

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scholarly article

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10.1084/JEM.20050914

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8

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202

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7536887

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16230478

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Toll-like receptor

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2213213

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