Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis.
about
mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosisRibosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to FunctionSeizure-dependent mTOR activation in 5-HT neurons promotes autism-like behaviors in miceA neuroprotective phase precedes striatal degeneration upon nucleolar stress.A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficitsKainic Acid Induces mTORC1-Dependent Expression of Elmo1 in Hippocampal Neurons.Activation of extracellular regulated kinase and mechanistic target of rapamycin pathway in focal cortical dysplasia.Does abnormal glycogen structure contribute to increased susceptibility to seizures in epilepsy?A voltage-gated calcium channel regulates lysosomal fusion with endosomes and autophagosomes and is required for neuronal homeostasisRapamycin Inhibition of mTOR Reduces Levels of the Na+/H+ Exchanger 3 in Intestines of Mice and Humans, Leading to Diarrhea.New drug classes for the treatment of partial onset epilepsy: focus on perampanel.Autophagy: regulation and role in developmentHigh-dose rapamycin blocks mossy fiber sprouting but not seizures in a mouse model of temporal lobe epilepsy.Autophagy in axonal and dendritic degeneration.Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex.mTOR inhibitors as a new therapeutic option for epilepsy.Autophagy and amino acid metabolism in the brain: implications for epilepsy.The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations.mTOR inhibition in epilepsy: rationale and clinical perspectives.Pathogenesis of Lafora Disease: Transition of Soluble Glycogen to Insoluble Polyglucosan.Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism.Autophagy in acute brain injury.Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.miR-96 attenuates status epilepticus-induced brain injury by directly targeting Atg7 and Atg16L1.Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury.Cleaning up epilepsy and neurodegeneration: the role of autophagy in epileptogenesisRecombinant Human Erythropoietin Protects Against Hippocampal Damage in Developing Rats with Seizures by Modulating Autophagy via the S6 Protein in a Time-Dependent Manner.Curcumin protects neuronal cells against status-epilepticus-induced hippocampal damage through induction of autophagy and inhibition of necroptosis.Less is more: Caloric regulation of neurogenesis and adult brain function.Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy.
P2860
Q24294367-B7382ED0-1817-48A7-A204-AE17291FC61EQ26770762-1B948E0C-B407-4BB2-928F-678298CF4CF6Q27308143-009669CD-7CA9-4D71-B62B-B47F44777180Q30549660-C76D66AC-088E-4899-8463-EC1069ED52C7Q30597707-DFE1845B-EC55-46C9-8484-01FCAD0C1210Q33559297-D67E59E0-C826-4C74-8EA2-1D96D68D4FD3Q33763506-6471055B-75DC-4A52-99CB-ECEF24BAA053Q34214636-A082C8AC-C6EB-43B7-BC8C-A904BBE5C3E4Q35219922-EA208177-85F1-4713-B943-2F81DD0DEAF8Q36848529-1227FCB1-2DC2-46C2-89D1-5D8A1353ADE1Q37014640-949AAAFF-F454-42CA-8808-40D52014EBCAQ37043057-8EFE405A-CC71-4D8D-BDCC-AB736F30BDF6Q37161103-A4887DB1-93C3-45E7-859C-44A561723333Q37208557-DC939818-F4E5-491A-85E0-2940E533C6CDQ37364126-AEA83B19-3262-4B24-A210-DC2D84ADF090Q38112211-8B8B6A04-5B40-4C0D-AE1B-93101036E353Q38242039-61278020-D4D1-4803-A5B8-4488234D148BQ38248845-B96528DA-5294-4223-956D-AB296D803413Q38336887-FD997E6D-F34C-4335-901C-76C3D7ECF232Q38628962-2294BEB9-6C23-4516-BB83-D5C93578B015Q38682634-FEB67ED7-777C-4F93-8BCD-BF0AB4E08960Q38852246-5568346C-C8B9-4B09-9416-BDE8CFCF0397Q39321120-FA1EC354-361B-4BC5-A4A9-A890091BFA30Q41580137-2FB5F9B5-212E-4E96-A199-3FD3B1ACB430Q41611849-CC0DEFBE-30D1-4C10-96AB-572B3A265120Q42585750-13351CC0-B247-464A-A3A9-278C514F3BD5Q47295294-6F010685-D927-4497-A785-A7C694E68334Q47333101-F063F90C-ECA6-4519-B203-7E5DFD289D97Q48167921-967B6B61-7F91-4587-86B8-19AA3B9CFE09Q51738955-51C9B72A-B5A1-4FC4-8B50-D966741DE16C
P2860
Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Impaired autophagy in neurons ...... ntribution to epileptogenesis.
@ast
Impaired autophagy in neurons ...... ntribution to epileptogenesis.
@en
type
label
Impaired autophagy in neurons ...... ntribution to epileptogenesis.
@ast
Impaired autophagy in neurons ...... ntribution to epileptogenesis.
@en
prefLabel
Impaired autophagy in neurons ...... ntribution to epileptogenesis.
@ast
Impaired autophagy in neurons ...... ntribution to epileptogenesis.
@en
P2093
P2860
P1476
Impaired autophagy in neurons ...... ntribution to epileptogenesis.
@en
P2093
Jiang Qian
John McMahon
Xiaoxing Huang
Xinjun Zhu
Yunfei Huang
Zhenyu Yue
P2860
P304
15704-15714
P356
10.1523/JNEUROSCI.2392-12.2012
P407
P577
2012-11-01T00:00:00Z