Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
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Molecular definitions of autophagy and related processes.Autophagy-regulating protease Atg4: structure, function, regulation and inhibition.Strategies for the etiological therapy of cystic fibrosis.Mitochondrial Ca2+ transport in the endothelium: regulation by ions, redox signalling and mechanical forces.Unveiling the role of VPS34 kinase domain dynamics in regulation of the autophagic PI3K complex.Coronarin D induces reactive oxygen species-mediated cell death in human nasopharyngeal cancer cells through inhibition of p38 MAPK and activation of JNK.Epigenetic Treatment of Neurodegenerative Ophthalmic Disorders: An Eye Toward the Future.Histone Deacetylase Inhibitor-Induced Autophagy in Tumor Cells: Implications for p53.ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammation.Biophysical characterization of Atg11, a scaffold protein essential for selective autophagy in yeast.Autophagy and inflammation in chronic respiratory disease.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.Immune recognition of irradiated cancer cells.Emerging roles of transcriptional programs in autophagy regulation.Enhancement of hepatic autophagy increases ureagenesis and protects against hyperammonemia.Lysosome-targeting agents in cancer therapy.Norcantharidin alone or in combination with crizotinib induces autophagic cell death in hepatocellular carcinoma by repressing c-Met-mTOR signaling.Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8.In vitro and in vivo effects of MK2206 and chloroquine combination therapy on endometriosis: Autophagy may be required for regrowth of endometriosis.The spectrum of T cell metabolism in health and disease.To be or not to be cell autonomous? Autophagy says both.Autophagy and T cell metabolism.Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survival.4-PBA ameliorates cellular homeostasis in fibroblasts from osteogenesis imperfecta patients by enhancing autophagy and stimulating protein secretion.Evaluation of autophagy inducers in epithelial cells carrying the ΔF508 mutation of the cystic fibrosis transmembrane conductance regulator CFTR.Filamentous Aggregation of Sequestosome-1/p62 in Brain Neurons and Neuroepithelial Cells upon Tyr-Cre-Mediated Deletion of the Autophagy Gene Atg7.NF-κB Signalling in Glioblastoma.Autophagy Modulation in Cancer: Current Knowledge on Action and Therapy.Can modulators of apolipoproteinB biogenesis serve as an alternate target for cholesterol-lowering drugs?β-Cell Autophagy in Diabetes Pathogenesis.p53-Mediated Molecular Control of Autophagy in Tumor Cells.Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy.Casein kinase 1α: biological mechanisms and theranostic potential.Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I.Till Death Do Us Part: The Marriage of Autophagy and Apoptosis.Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity.Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan.AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells.Role of the Inflammation-Autophagy-Senescence Integrative Network in Osteoarthritis.Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics
P2860
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P2860
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年学术文章
@wuu
2017年学术文章
@zh-cn
2017年学术文章
@zh-hans
2017年学术文章
@zh-my
2017年学术文章
@zh-sg
2017年學術文章
@yue
2017年學術文章
@zh
2017年學術文章
@zh-hant
name
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
@en
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
@nl
type
label
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
@en
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
@nl
prefLabel
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
@en
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
@nl
P2860
P50
P356
P1476
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.
@en
P2093
Beth Levine
Lorenzo Galluzzi
P2860
P2888
P304
P356
10.1038/NRD.2017.22
P577
2017-05-19T00:00:00Z
P6179
1085439789