A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes.
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G protein-coupled receptors form stable complexes with inwardly rectifying potassium channels and adenylyl cyclaseA recombinant inwardly rectifying potassium channel coupled to GTP-binding proteinsThe selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic systemFunctional characterization of vasopressin type 2 receptor substitutions (R137H/C/L) leading to nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis: implications for treatments.Inhibition of function in Xenopus oocytes of the inwardly rectifying G-protein-activated atrial K channel (GIRK1) by overexpression of a membrane-attached form of the C-terminal tail.Graded contribution of the Gbeta gamma binding domains to GIRK channel activation.Cloning, tissue distribution, and functional expression of the human G protein beta 4-subunit.A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.Evidence that neuronal G-protein-gated inwardly rectifying K+ channels are activated by G beta gamma subunits and function as heteromultimers.Single channel analysis of the regulation of GIRK1/GIRK4 channels by protein phosphorylation.Engineering of an artificial light-modulated potassium channel.G protein-coupled receptor signaling to Kir channels in Xenopus oocytes.gp120 envelope glycoproteins of human immunodeficiency viruses competitively antagonize signaling by coreceptors CXCR4 and CCR5Heterologous facilitation of G protein-activated K(+) channels by beta-adrenergic stimulation via cAMP-dependent protein kinaseRGS proteins reconstitute the rapid gating kinetics of gbetagamma-activated inwardly rectifying K+ channels.Supramolecular assemblies and localized regulation of voltage-gated ion channels.Antisense oligonucleotides against receptor kinase GRK2 disrupt target selectivity of beta-adrenergic receptors in atrial myocytes.New roles for RGS2, 5 and 8 on the ratio-dependent modulation of recombinant GIRK channels expressed in Xenopus oocytes.Regulation of cardiac L-type Ca2+ channel by coexpression of G(alpha s) in Xenopus oocytes.Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.Differential dissociation of G protein heterotrimers.Co-expression of Gbeta5 enhances the function of two Ggamma subunit-like domain-containing regulators of G protein signaling proteins.Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K+ channel by GalphaiGDP and Gbetagamma.Heterologous expression and coupling of G protein-gated inwardly rectifying K+ channels in adult rat sympathetic neurons.Galphai3 primes the G protein-activated K+ channels for activation by coexpressed Gbetagamma in intact Xenopus oocytes.Gbeta residues that do not interact with Galpha underlie agonist-independent activity of K+ channels.Redox-dependent gating of G protein-coupled inwardly rectifying K+ channels.Overexpression of beta 1 and beta 2 adrenergic receptors in rat atrial myocytes. Differential coupling to G protein-gated inward rectifier K(+) channels via G(s) and G(i)/o.Galphai1 and Galphai3 differentially interact with, and regulate, the G protein-activated K+ channel.Characterization of a hyperpolarization-activated time-dependent potassium current in canine cardiomyocytes from pulmonary vein myocardial sleeves and left atrium.The sensitivity of G protein-activated K+ channels toward halothane is essentially determined by the C terminus.Evidence for a functional interaction between integrins and G protein-activated inward rectifier K+ channels.Identification of a potassium channel site that interacts with G protein betagamma subunits to mediate agonist-induced signaling.Ion Channels as Reporters of Membrane Receptor Function: Automated Analysis in Xenopus Oocytes.Activation of muscarinic K+ current by beta-adrenergic receptors in cultured atrial myocytes transfected with beta1 subunit of heterotrimeric G proteins.RGS proteins maintain robustness of GPCR-GIRK coupling by selective stimulation of the G protein subunit Gαo.Probing the G-protein regulation of GIRK1 and GIRK4, the two subunits of the KACh channel, using functional homomeric mutants.Activation of G protein-coupled inward rectifier K+ channels in brain neurons requires association of G protein beta gamma subunits with cell membrane.Desensitization of inositol 1,4,5-trisphosphate/Ca2+-induced Cl- currents by prolonged activation of G proteins in Xenopus oocytes.The K+ channel inward rectifier subunits form a channel similar to neuronal G protein-gated K+ channel.
P2860
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P2860
A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
A G protein-gated K channel is ...... a subunits in Xenopus oocytes.
@ast
A G protein-gated K channel is ...... a subunits in Xenopus oocytes.
@en
type
label
A G protein-gated K channel is ...... a subunits in Xenopus oocytes.
@ast
A G protein-gated K channel is ...... a subunits in Xenopus oocytes.
@en
prefLabel
A G protein-gated K channel is ...... a subunits in Xenopus oocytes.
@ast
A G protein-gated K channel is ...... a subunits in Xenopus oocytes.
@en
P2093
P2860
P356
P1476
A G protein-gated K channel is ...... a subunits in Xenopus oocytes.
@en
P2093
P2860
P304
P356
10.1085/JGP.105.3.421
P577
1995-03-01T00:00:00Z