Natural bile acids and synthetic analogues modulate large conductance Ca2+-activated K+ (BKCa) channel activity in smooth muscle cells.
about
The steroid interaction site in transmembrane domain 2 of the large conductance, voltage- and calcium-gated potassium (BK) channel accessory β1 subunitCerebrovascular dilation via selective targeting of the cholane steroid-recognition site in the BK channel β1-subunit by a novel nonsteroidal agentCirculating bile acids predict outcome in critically ill patients.Effects of deoxycholylglycine, a conjugated secondary bile acid, on myogenic tone and agonist-induced contraction in rat resistance arteriesCalcium- and voltage-gated potassium (BK) channel activators in the 5β-cholanic acid-3α-ol analogue series with modifications in the lateral chainPrimary sclerosing cholangitis: updates in diagnosis and therapyMulti-generational pharmacophore modeling for ligands to the cholane steroid-recognition site in the β₁ modulatory subunit of the BKCa channelActivation of calcium- and voltage-gated potassium channels of large conductance by leukotriene B4Bile Acid Inhibition of N-type Calcium Channel Currents from Sympathetic Ganglion NeuronsHydrophobic bile acids relax rat detrusor contraction via inhibiting the opening of the Na⁺/Ca²⁺ exchanger.Shock releases bile acid inducing platelet inhibition and fibrinolysisStructural determinants of monohydroxylated bile acids to activate beta 1 subunit-containing BK channelsBile acids regulate cardiovascular functionOverexcited MaxiK and KATP channels underlie obstructive jaundice-induced vasoconstrictor hyporeactivity of arterial smooth muscle.BK channels in rat and human pulmonary smooth muscle cells are BKα-β1 functional complexes lacking the oxygen-sensitive stress axis regulated exon insert.A little humour relaxes the gallbladder.Decoding the vasoregulatory activities of bile acid-activated receptors in systemic and portal circulation: role of gaseous mediators.Bile acids and cardiovascular function in cirrhosis.Serum bile acids as marker for acute decompensation and acute-on-chronic liver failure in patients with non-cholestatic cirrhosis.The second transmembrane domain of the large conductance, voltage- and calcium-gated potassium channel beta(1) subunit is a lithocholate sensor.Bile Acids Do Not Contribute to the Altered Calcium Homeostasis of Platelets from Rats with Biliary Cirrhosis.Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels.Beta2 and beta4 subunits of BK channels confer differential sensitivity to acute modulation by steroid hormones.Bile acids increase the activity of the epithelial Na+ channel.Bile acids induce arrhythmias in human atrial myocardium--implications for altered serum bile acid composition in patients with atrial fibrillation.Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice
P2860
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P2860
Natural bile acids and synthetic analogues modulate large conductance Ca2+-activated K+ (BKCa) channel activity in smooth muscle cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Natural bile acids and synthet ...... tivity in smooth muscle cells.
@ast
Natural bile acids and synthet ...... tivity in smooth muscle cells.
@en
type
label
Natural bile acids and synthet ...... tivity in smooth muscle cells.
@ast
Natural bile acids and synthet ...... tivity in smooth muscle cells.
@en
prefLabel
Natural bile acids and synthet ...... tivity in smooth muscle cells.
@ast
Natural bile acids and synthet ...... tivity in smooth muscle cells.
@en
P2093
P2860
P356
P1476
Natural bile acids and synthet ...... tivity in smooth muscle cells.
@en
P2093
Alejandro M Dopico
John V Walsh
Joshua J Singer
P2860
P304
P356
10.1085/JGP.20028537
P577
2002-03-01T00:00:00Z