Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.
about
RNAi screens identify CHD4 as an essential gene in breast cancer growth.The interplay between cell signalling and the mevalonate pathway in cancer.Molecular mechanisms linking geranylgeranyl diphosphate synthase to cell survival and proliferation.Stromal regulation of prostate cancer cell growth by mevalonate pathway enzymes HMGCS1 and HMGCR.Cilia loss sensitizes cells to transformation by activating the mevalonate pathway.Overexpression and RNA interference of TwDXR regulate the accumulation of terpenoid active ingredients in Tripterygium wilfordii.Insensitivity to atorvastatin is associated with increased accumulation of intracellular lipid droplets and fatty acid metabolism in breast cancer cells.
P2860
Q36173845-29517D85-1EB2-4013-A709-AF258C57BF7CQ38937455-4DD720B9-7EE2-4C33-97E0-C0CFF58DF68BQ41162635-699877B6-CF68-40A3-AA1A-7F032092FF3AQ44322819-14971794-6276-47BD-9516-E5439D9A3341Q48122685-7A7A7AA9-5D6F-4022-BD91-9D15ED5878E4Q48360910-F57F6BD9-4433-4A55-9CA0-67E9F3602D13Q52721904-BAD593EB-3449-4A3E-B910-8EF4701467FB
P2860
Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Genome-wide RNAi analysis reve ...... potentiates tumor cell death.
@ast
Genome-wide RNAi analysis reve ...... potentiates tumor cell death.
@en
type
label
Genome-wide RNAi analysis reve ...... potentiates tumor cell death.
@ast
Genome-wide RNAi analysis reve ...... potentiates tumor cell death.
@en
prefLabel
Genome-wide RNAi analysis reve ...... potentiates tumor cell death.
@ast
Genome-wide RNAi analysis reve ...... potentiates tumor cell death.
@en
P2093
P2860
P50
P356
P1433
P1476
Genome-wide RNAi analysis reve ...... s potentiates tumor cell death
@en
P2093
Aleksandra A Pandyra
Carolyn A Goard
Elke Ericson
Guri Giaever
Janice T Pong
Karl S Lang
Kevin R Brown
Marinella Gebbia
Peter J Mullen
Rosemary Yu
P2860
P304
26909-26921
P356
10.18632/ONCOTARGET.4817
P407
P577
2015-09-01T00:00:00Z