Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer - Wikidata - awgldk - TriplyDB

Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer

Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer

http://www.wikidata.org/entity/Q36414044

about

Multifunctional DDX3: dual roles in various cancer development and its related signaling pathways DDX3, a potential target for cancer treatment Coupling between the DEAD-box RNA helicases Ded1p and eIF4A DDX3 promotes tumor invasion in colorectal cancer via the CK1ε/Dvl2 axis.DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma.DDX3 enhances oncogenic KRAS‑induced tumor invasion in colorectal cancer via the β‑catenin/ZEB1 axis.DDX3X promotes the biogenesis of a subset of miRNAs and the potential roles they played in cancer development.The prognostic effect of DDX3 upregulation in distant breast cancer metastases.Combination treatment using DDX3 and PARP inhibitors induces synthetic lethality in BRCA1-proficient breast cancer.RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3 Protein-protein interaction analysis for functional characterization of helicases.Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.Nucleic acid sensing pattern recognition receptors in the development of colorectal cancer and colitis.Nuclear DDX3 expression predicts poor outcome in colorectal and breast cancer.(DEAD)-box RNA helicase 3 modulates NF-κB signal pathway by controlling the phosphorylation of PP2A-C subunit.DDX3 localizes to the centrosome and prevents multipolar mitosis by epigenetically and translationally modulating p53 expression.Targeting mitochondrial translation by inhibiting DDX3: a novel radiosensitization strategy for cancer treatment.Targeting RNA helicases in cancer: The translation trap.Role of DDX3 in the pathogenesis of inflammatory bowel disease.Revealing dynamics of helicase translocation on single-stranded DNA using high-resolution nanopore tweezers.Global Effects of DDX3 Inhibition on Cell Cycle Regulation Identified by a Combined Phosphoproteomics and Single Cell Tracking Approach.Differential miRNA expression profiling reveals miR-205-3p to be a potential radiosensitizer for low- dose ionizing radiation in DLD-1 cells.DDX3X RNA helicase affects breast cancer cell cycle progression by regulating expression of KLF4 Abnormal expression of YEATS4 associates with poor prognosis and promotes cell proliferation of hepatic carcinoma cell by regulation the TCEA1/DDX3 axis

P2860

Q26749143-48E45845-6BD9-43D4-B90C-1AB88F2E0186 Q26779054-8BEBB807-933B-4E14-88B7-E50A86F458BF Q27468894-BF97CC5D-3C2C-40B6-AAA3-FE9A2B743797 Q36595592-5EB99A23-885E-44B4-9D03-C9F085E0870E Q37040124-7632AA46-5252-4E6F-B8A5-0AFFE401ABB2 Q37225645-F0CB0300-B22B-42F2-879C-FED013CB189F Q37227844-9F5F6CA4-D079-4C67-A381-8A94D2C380D0 Q37617548-9E66B493-87AD-405F-9BDC-5027F38538BA Q38718686-FD91860E-4D39-4B31-9735-D9588E19F3AB Q38734333-2D5600FA-903A-4573-BE83-42B62ED8D289 Q38811108-855C642E-3D70-494B-A6E0-35A3C5917C36 Q38998990-884978C4-859F-4D4D-84D3-C639C37C200F Q39146122-F518F169-919D-430F-BF42-FCCF2C3A7733 Q40100476-80CA9680-DAB0-41BE-826A-273AC1A6CFC5 Q40246228-42CB8DFE-E943-47C1-8788-A8881AD8746F Q41534142-85372419-259C-4116-A07D-7ED72B365CAE Q46312467-DF7FD40F-903D-44D4-98B7-6C1C6B793591 Q47719079-73AC4D1A-5AE8-4650-A360-1BD78C6A10C5 Q49569343-A8C3746A-76FA-4F35-8D61-3118F84C1ABD Q50097700-8838A96B-9AFB-4013-A559-FC4D0BBC71CF Q52717362-4A997C4A-39CF-4917-8FFE-10E0A6F939F2 Q55155695-3A6A6E97-59AC-431B-8013-5A6F6EB6AD1F Q57753756-F3B47AC0-F0E6-4890-8DEA-BF31D7C2EE30 Q58790046-7F01836B-48EC-402F-80C6-4CBD704CE6DB

P2860

Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer

http://www.wikidata.org/entity/Q36414044

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年学术文章

@wuu

2015年学术文章

@zh-cn

2015年学术文章

@zh-hans

2015年学术文章

@zh-my

2015年学术文章

@zh-sg

2015年學術文章

@yue

2015年學術文章

@zh

2015年學術文章

@zh-hant

name

Identification of the DEAD box ...... ic target in colorectal cancer

@ast

Identification of the DEAD box ...... ic target in colorectal cancer

@en

type

label

Identification of the DEAD box ...... ic target in colorectal cancer

@ast

Identification of the DEAD box ...... ic target in colorectal cancer

@en

prefLabel

Identification of the DEAD box ...... ic target in colorectal cancer

@ast

Identification of the DEAD box ...... ic target in colorectal cancer

@en

P1433

Q36414044-49C32E49-C2F5-4891-A128-7280ED976D28

P1476

Q36414044-8EAAFCE3-DFC6-416D-BE06-7C5FA8C2882F

P2093

Q36414044-082FC62D-7513-4FA9-BEB3-C083C396BF31

Q36414044-0A12A44E-F027-444F-B59B-78BCE680B4E7

Q36414044-3BFEB3DB-1302-4AA4-A6C9-BB60FCBAE402

Q36414044-6510CE73-5967-4327-B09D-DE354EA56E19

Q36414044-92705A86-02BD-48AB-8DA9-72C023F39305

Q36414044-97E9C0DB-C6ED-4979-AA2F-7EC422B7C4AD

Q36414044-BD3F3E25-DF90-4217-815D-027F2754D054

Q36414044-E50D81BF-CEDF-41CB-9383-B5760347F126

Q36414044-F44FB69B-771E-416F-98D4-FD78536A1771

Q36414044-F98CE9A7-82F3-4A4E-A931-EA747A13A7E6

P2860

Q36414044-06570D4B-9A57-4275-9226-C6AE37EAC250

Q36414044-065D7422-0ACA-4C32-8A65-9885ED31DE42

Q36414044-0B403011-360F-4DD8-83A5-E874478DD62F

Q36414044-0E7F4623-15B4-4A50-A723-22C9BD35D3A1

Q36414044-1DF956DF-CC93-4D02-A9FB-AE16A62F20A5

Q36414044-1E17CACA-4588-4DA7-80ED-557B645EABC0

Q36414044-2A355E0F-CA46-49BC-82C7-C450DD6BAF6E

Q36414044-2CEFA13F-383D-4507-A126-60EA95BD7946

Q36414044-46F72E93-D3E3-4C49-96F4-8A71B6345CDC

Q36414044-47C94DC6-A1B2-4B15-9F4A-D48D9C0BD9CA

P304

Q36414044-E0005BDA-B581-4E7F-AB1B-F0C0AFFE69A0

P31

Q36414044-44BAF98C-701E-4557-BF91-A074DC9BE1BE

P356

Q36414044-C1F612C1-2BFE-4CA3-B715-FCF348DA0F58

P407

Q36414044-C9A738FB-B444-4D88-96B2-33317A7D5CFA

P433

Q36414044-0486F901-09CC-45E7-866F-E724138BB73B

P478

Q36414044-BE3CBA03-27C8-4628-AB52-C5E84459C1B6

P50

Q36414044-6BD54964-B781-4991-B090-326422379EFD

Q36414044-F5BFB040-7499-4926-87D5-54FCB5BDCBC4

P577

Q36414044-6D91FECC-CB61-4927-A929-73DD6B7BD116

P698

Q36414044-943BE05F-097C-4FE6-99A3-959743D5E441

P921

Q36414044-FD9134F8-0488-47BE-92D0-66E8366193DF

P932

Q36414044-E6754ED9-48A2-47E4-BD2F-94EC97F9802E

P356

ONCOTARGET.4873

P1433

P1476

Identification of the DEAD box ...... ic target in colorectal cancer

@en

P2093

Cynthia Berlinicke

http://www.w3.org/2001/XMLSchema#string

Elsken van der Wall

http://www.w3.org/2001/XMLSchema#string

G Johan Offerhaus

http://www.w3.org/2001/XMLSchema#string

Horst Bürger

http://www.w3.org/2001/XMLSchema#string

Justin Brilliant

http://www.w3.org/2001/XMLSchema#string

Kari Trumpi

http://www.w3.org/2001/XMLSchema#string

Onno Kranenburg

http://www.w3.org/2001/XMLSchema#string

Paul J van Diest

http://www.w3.org/2001/XMLSchema#string

Venu Raman

http://www.w3.org/2001/XMLSchema#string

Wendy de Leng

http://www.w3.org/2001/XMLSchema#string

P2860

DDX3, a DEAD box RNA helicase with tumor growth-suppressive property and transcriptional regulation activity of the p21waf1/cip1 promoter, is a candidate tumor suppressor

DDX3, a DEAD box RNA helicase, is deregulated in hepatitis virus-associated hepatocellular carcinoma and is involved in cell growth control

DDX3 regulates cell growth through translational control of cyclin E1

The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

Identification of an antiapoptotic protein complex at death receptors

Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response

Dissecting the genomic complexity underlying medulloblastoma

Comprehensive molecular characterization of human colon and rectal cancer

Statistical analysis of real-time PCR data

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

P304

28312-28326

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.18632/ONCOTARGET.4873

http://www.w3.org/2001/XMLSchema#string

P407

P433

29

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

Marise R Heerma van Voss

P577

2015-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26311743

http://www.w3.org/2001/XMLSchema#string

P921

colorectal cancer

P932

4695062

http://www.w3.org/2001/XMLSchema#string