Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability.
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Circadian dysfunction may be a key component of the non-motor symptoms of Parkinson's disease: insights from a transgenic mouse modelBK Channels in the Central Nervous System.Quantitative localization of Cav2.1 (P/Q-type) voltage-dependent calcium channels in Purkinje cells: somatodendritic gradient and distinct somatic coclustering with calcium-activated potassium channels.BK channels regulate sinoatrial node firing rate and cardiac pacing in vivoBK Channels Localize to the Paranodal Junction and Regulate Action Potentials in Myelinated Axons of Cerebellar Purkinje Cells.Generation of Kcnma1fl-tdTomato, a conditional deletion of the BK channel α subunit in mouse.Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons.The Circadian Clock Gene Period1 Connects the Molecular Clock to Neural Activity in the Suprachiasmatic Nucleus.Mis-expression of the BK K(+) channel disrupts suprachiasmatic nucleus circuit rhythmicity and alters clock-controlled behavior.BK channel inactivation gates daytime excitability in the circadian clock.Properties of Slo1 K+ channels with and without the gating ring.Phosphorylation of a constitutive serine inhibits BK channel variants containing the alternate exon "SRKR".Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability.Survival and growth of C57BL/6J mice lacking the BK channel, Kcnma1: lower adult body weight occurs together with higher body fat.Blurring the boundaries: developmental and activity-dependent determinants of neural circuits.Membrane Currents, Gene Expression, and Circadian Clocks.Multilevel regulation: Controlling BK channels in central clock neurons.Knockout of the BK β4-subunit promotes a functional coupling of BK channels and ryanodine receptors that mediate a fAHP-induced increase in excitability.A voltage-dependent K+ channel in the lysosome is required for refilling lysosomal Ca2+ stores.Novel description of the large conductance Ca2+-modulated K+ channel current, BK, during an action potential from suprachiasmatic nucleus neurons.Downregulation of KCNMB4 expression and changes in BK channel subtype in hippocampal granule neurons following seizure activity.A role for corticotropin-releasing factor signaling in the lateral habenula and its modulation by early-life stress.Potassium Channel Gain of Function in Epilepsy: An Unresolved Paradox.
P2860
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P2860
Genetic activation of BK currents in vivo generates bidirectional effects on neuronal excitability.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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name
Genetic activation of BK curre ...... ects on neuronal excitability.
@ast
Genetic activation of BK curre ...... ects on neuronal excitability.
@en
type
label
Genetic activation of BK curre ...... ects on neuronal excitability.
@ast
Genetic activation of BK curre ...... ects on neuronal excitability.
@en
prefLabel
Genetic activation of BK curre ...... ects on neuronal excitability.
@ast
Genetic activation of BK curre ...... ects on neuronal excitability.
@en
P2860
P356
P1476
Genetic activation of BK curre ...... fects on neuronal excitability
@en
P2093
Jenna R Montgomery
P2860
P304
18997-19002
P356
10.1073/PNAS.1205573109
P407
P577
2012-10-29T00:00:00Z