Chemoprotection by sulforaphane: keep one eye beyond Keap1. - Wikidata - awgldk - TriplyDB

Chemoprotection by sulforaphane: keep one eye beyond Keap1.

Chemoprotection by sulforaphane: keep one eye beyond Keap1.

http://www.wikidata.org/entity/Q36415068

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Dietary histone deacetylase inhibitors: from cells to mice to man Mechanisms of action of isothiocyanates in cancer chemoprevention: an update Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.Human gut bacterial communities are altered by addition of cruciferous vegetables to a controlled fruit- and vegetable-free diet.Epigenetic mechanisms underlying diet-sourced compounds in the prevention and treatment of gastrointestinal cancer Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells Development of Neh2-luciferase reporter and its application for high throughput screening and real-time monitoring of Nrf2 activators.Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli.Differential modulation of keratin expression by sulforaphane occurs via Nrf2-dependent and -independent pathways in skin epithelia.Sulforaphane increases drug-mediated cytotoxicity toward cancer stem-like cells of pancreas and prostate.Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon.Multi-targeted prevention of cancer by sulforaphane.Dietary manipulation of histone structure and function.Cruciferous vegetable consumption and lung cancer risk: a systematic review.The broccoli-born isothiocyanate sulforaphane impairs nucleotide excision repair: XPA as one potential target.Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1.Variation of glucoraphanin metabolism in vivo and ex vivo by human gut bacteria.Isothiocyanates reduce mercury accumulation via an Nrf2-dependent mechanism during exposure of mice to methylmercury.Metabolism as a key to histone deacetylase inhibition.Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention.Nonhistone protein acetylation as cancer therapy targets.Sulforaphane Suppresses Hepatitis C Virus Replication by Up-Regulating Heme Oxygenase-1 Expression through PI3K/Nrf2 Pathway.Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha.Chemoprevention of 1,2-dimethylhydrazine-induced colonic preneoplastic lesions in Fischer rats by 6-methylsulfinylhexyl isothiocyanate, a wasabi derivative.Sulforaphane inhibits multiple inflammasomes through an Nrf2-independent mechanism Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.Transcriptomic and proteomic profiling of KEAP1 disrupted and sulforaphane-treated human breast epithelial cells reveals common expression profiles.Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes.NF-kappaB and Nrf2 as prime molecular targets for chemoprevention and cytoprotection with anti-inflammatory and antioxidant phytochemicals.Discovery and development of sulforaphane as a cancer chemopreventive phytochemical.Antiproliferative activity of sulforaphane in Akt-overexpressing ovarian cancer cells.Technologies and experimental approaches at the National Institutes of Health Botanical Research Centers.Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.Advances in the proteomic discovery of novel therapeutic targets in cancer.Sulforaphane is a Nrf2-independent inhibitor of mitochondrial fission Targeting oxidative stress in cancer.

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P2860

Chemoprotection by sulforaphane: keep one eye beyond Keap1.

http://www.wikidata.org/entity/Q36415068

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2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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2006年學術文章

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2006年學術文章

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Chemoprotection by sulforaphane: keep one eye beyond Keap1.

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Chemoprotection by sulforaphane: keep one eye beyond Keap1.

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Chemoprotection by sulforaphane: keep one eye beyond Keap1.

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Chemoprotection by sulforaphane: keep one eye beyond Keap1.

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Chemoprotection by sulforaphane: keep one eye beyond Keap1.

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Chemoprotection by sulforaphane: keep one eye beyond Keap1.

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J.CANLET.2005.02.033

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Chemoprotection by sulforaphane: keep one eye beyond Keap1.

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Melinda C Myzak

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Roderick H Dashwood

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P2860

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors.

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates

Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Electrophile and antioxidant regulation of enzymes that detoxify carcinogens

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitors.

Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis.

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