Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region
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Gating Movement of Acetylcholine Receptor Caught by Plunge-FreezingA single beta subunit M2 domain residue controls the picrotoxin sensitivity of alphabeta heteromeric glycine receptor chloride channels.Homologous mutations on different subunits cause unequal but additive effects on n-alcohol block in the nicotinic receptor poreStructural effects of quinacrine binding in the open channel of the acetylcholine receptor.Charge scan reveals an extended region at the intracellular end of the GABA receptor pore that can influence ion selectivity.Monovalent and divalent cation permeability and block of neuronal nicotinic receptor channels in rat parasympathetic gangliaState-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor. Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit.Asymmetric and independent contribution of the second transmembrane segment 12' residues to diliganded gating of acetylcholine receptor channels: a single-channel study with choline as the agonistPermeability of wild-type and mutant cystic fibrosis transmembrane conductance regulator chloride channels to polyatomic anions.On the structural basis for size-selective permeation of organic cations through the voltage-gated sodium channel. Effect of alanine mutations at the DEKA locus on selectivity, inhibition by Ca2+ and H+, and molecular sievingMutations at two distinct sites within the channel domain M2 alter calcium permeability of neuronal alpha 7 nicotinic receptor.The extracellular linker of muscle acetylcholine receptor channels is a gating control element.Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity.Charge selectivity of the designed uncharged peptide ion channel Ac-(LSSLLSL)3-CONH2.Molecular dissection of Cl--selective Cys-loop receptor points to components that are dispensable or essential for channel activity.Dynamic properties of Na+ ions in models of ion channels: a molecular dynamics study.Pores formed by the nicotinic receptor m2delta Peptide: a molecular dynamics simulation study.A single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptorMutations at the GABA receptor selectivity filter: a possible role for effective charges.A putative selectivity filter in the G-protein-coupled receptors for parathyroid hormone and secretion.Luminal and non-luminal non-competitive inhibitor binding sites on the nicotinic acetylcholine receptor.Assigning functions to residues in the acetylcholine receptor channel region (review).Molecular dynamics study of water and Na+ ions in models of the pore region of the nicotinic acetylcholine receptor.The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics.Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis.Identification of a region of strong discrimination in the pore of CFTR.Chimeric mutations in the M2 segment of the 5-hydroxytryptamine-gated chloride channel MOD-1 define a minimal determinant of anion/cation permeability.
P2860
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P2860
Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region
description
1992 nî lūn-bûn
@nan
1992年の論文
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1992年学术文章
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1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
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1992年學術文章
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name
Tris+/Na+ permeability ratios ...... acellular end of the M2 region
@ast
Tris+/Na+ permeability ratios ...... acellular end of the M2 region
@en
type
label
Tris+/Na+ permeability ratios ...... acellular end of the M2 region
@ast
Tris+/Na+ permeability ratios ...... acellular end of the M2 region
@en
prefLabel
Tris+/Na+ permeability ratios ...... acellular end of the M2 region
@ast
Tris+/Na+ permeability ratios ...... acellular end of the M2 region
@en
P2093
P2860
P356
P1476
Tris+/Na+ permeability ratios ...... acellular end of the M2 region
@en
P2093
P2860
P304
P356
10.1085/JGP.99.4.545
P50
P577
1992-04-01T00:00:00Z