Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity.
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A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channelPathways and Barriers for Ion Translocation through the 5-HT3A Receptor ChannelMolecular physiology of bestrophins: multifunctional membrane proteins linked to best disease and other retinopathiesFunctional characterization of a novel family of acetylcholine-gated chloride channels in Schistosoma mansoniPhilosophy of voltage-gated proton channelsVoltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) familyThe Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma.Determinants of anion permeation in the second transmembrane domain of the mouse bestrophin-2 chloride channel.Identifying the elusive link between amino acid sequence and charge selectivity in pentameric ligand-gated ion channels.Redesigning the monovalent cation specificity of an enzymeStructure and function of the glycine receptor and related nicotinicoid receptors.Theoretical studies of the M2 transmembrane segment of the glycine receptor: models of the open pore structure and current-voltage characteristics.Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability.Probing ion-channel pores one proton at a time.EXP-1 is an excitatory GABA-gated cation channel.HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation.Redesigning allosteric activation in an enzyme.A model of the glycine receptor deduced from Brownian dynamics studies.Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptorsSpillover transmission is mediated by the excitatory GABA receptor LGC-35 in C. elegansMolecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin.Charge selectivity of the Cys-loop family of ligand-gated ion channels.Charge scan reveals an extended region at the intracellular end of the GABA receptor pore that can influence ion selectivity.Inhibitory glycine receptors: an update.Single channel analysis of conductance and rectification in cation-selective, mutant glycine receptor channelsRescue of volume-regulated anion current by bestrophin mutants with altered charge selectivity.Anion-cation permeability correlates with hydrated counterion size in glycine receptor channels.Reversal of ion-charge selectivity renders the pentameric ligand-gated ion channel GLIC insensitive to anaestheticsThe structural basis of function in Cys-loop receptors.Synaptic neurotransmitter-gated receptorsEmerging approaches to probing ion channel structure and function.Chloride ions in the pore of glycine and GABA channels shape the time course and voltage dependence of agonist currents.Rings of charge within the extracellular vestibule influence ion permeation of the 5-HT3A receptor.Electrophysiological Signature of Homomeric and Heteromeric Glycine Receptor Channels.Agonist-dependent single channel current and gating in alpha4beta2delta and alpha1beta2gamma2S GABAA receptorsA single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptorMutations at the GABA receptor selectivity filter: a possible role for effective charges.Computational prediction of ion permeation characteristics in the glycine receptor modified by photo-sensitive compoundsLoose protein packing around the extracellular half of the GABA(A) receptor beta1 subunit M2 channel-lining segment.Two bestrophins cloned from Xenopus laevis oocytes express Ca(2+)-activated Cl(-) currents.
P2860
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P2860
Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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@zh-sg
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name
Cation-selective mutations in ...... nts of ion-charge selectivity.
@ast
Cation-selective mutations in ...... nts of ion-charge selectivity.
@en
type
label
Cation-selective mutations in ...... nts of ion-charge selectivity.
@ast
Cation-selective mutations in ...... nts of ion-charge selectivity.
@en
prefLabel
Cation-selective mutations in ...... nts of ion-charge selectivity.
@ast
Cation-selective mutations in ...... nts of ion-charge selectivity.
@en
P2860
P50
P356
P1476
Cation-selective mutations in ...... nts of ion-charge selectivity.
@en
P2093
Peter H Barry
P2860
P304
P356
10.1085/JGP.20028552
P577
2002-05-01T00:00:00Z