Functional role of the PE domain and immunogenicity of the Mycobacterium tuberculosis triacylglycerol hydrolase LipY.
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Identification and Characterization of Lipase Activity and Immunogenicity of LipL from Mycobacterium tuberculosisUnderstanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysisExperimental Models of Foamy Macrophages and Approaches for Dissecting the Mechanisms of Lipid Accumulation and Consumption during Dormancy and Reactivation of TuberculosisMycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophagesMmPPOX inhibits Mycobacterium tuberculosis lipolytic enzymes belonging to the hormone-sensitive lipase family and alters mycobacterial growthCharacterization of an acid inducible lipase Rv3203 from Mycobacterium tuberculosis H37RvHemolytic phospholipase Rv0183 of Mycobacterium tuberculosis induces inflammatory response and apoptosis in alveolar macrophage RAW264.7 cellsSrc homology 3-interacting domain of Rv1917c of Mycobacterium tuberculosis induces selective maturation of human dendritic cells by regulating PI3K-MAPK-NF-kappaB signaling and drives Th2 immune responsesA monoacylglycerol lipase from Mycobacterium smegmatis Involved in bacterial cell interactionMycobacterium tuberculosis lipolytic enzymes as potential biomarkers for the diagnosis of active tuberculosisMycobacterial PE/PPE proteins at the host-pathogen interface.Whole genome identification of Mycobacterium tuberculosis vaccine candidates by comprehensive data mining and bioinformatic analysesSerodiagnostic efficacy of Mycobacterium tuberculosis 30/32-kDa mycolyl transferase complex, ESAT-6, and CFP-10 in patients with active tuberculosisThe PE-PPE domain in mycobacterium reveals a serine α/β hydrolase fold and function: an in-silico analysisCaseation of human tuberculosis granulomas correlates with elevated host lipid metabolism.LipC (Rv0220) is an immunogenic cell surface esterase of Mycobacterium tuberculosis.Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall.Structure of the Mycobacterium tuberculosis type VII secretion system chaperone EspG5 in complex with PE25-PPE41 dimer.Comparative analyses of nonpathogenic, opportunistic, and totally pathogenic mycobacteria reveal genomic and biochemical variabilities and highlight the survival attributes of Mycobacterium tuberculosis.Human granuloma in vitro model, for TB dormancy and resuscitation.Low cost tuberculosis vaccine antigens in capsules: expression in chloroplasts, bio-encapsulation, stability and functional evaluation in vitro.The PE16 (Rv1430) of Mycobacterium tuberculosis is an esterase belonging to serine hydrolase superfamily of proteins.Identification of residues involved in substrate specificity and cytotoxicity of two closely related cutinases from Mycobacterium tuberculosisConserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway.Modulation of the Activity of Mycobacterium tuberculosis LipY by Its PE DomainPE11 (Rv1169c) selectively alters fatty acid components of Mycobacterium smegmatis and host cell interleukin-6 level accompanied with cell death.Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis.The perilipin-like PPE15 protein in Mycobacterium tuberculosis is required for triacylglycerol accumulation under dormancy-inducing conditions.Synthesis and kinetic evaluation of cyclophostin and cyclipostins phosphonate analogs as selective and potent inhibitors of microbial lipases.Mycobacterium tuberculosis Resists Stress by Regulating PE19 ExpressionBuruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans.Reversible lipid accumulation and associated division arrest of Mycobacterium avium in lipoprotein-induced foamy macrophages may resemble key events during latency and reactivation of tuberculosisLipid hydrolizing enzymes in virulence: Mycobacterium tuberculosis as a model system.Effects of surfactants on lipase structure, activity, and inhibition.The ins and outs of Mycobacterium tuberculosis protein export.Ins and outs of Mycobacterium tuberculosis PPE family in pathogenesis and implications for novel measures against tuberculosis.Role of glycans and glycoproteins in disease development by Mycobacterium tuberculosis.Modulation of Trehalose Dimycolate and Immune System by Rv0774c Protein Enhanced the Intracellular Survival of Mycobacterium smegmatis in Human Macrophages Cell LineCharacterization of LipN (Rv2970c) of Mycobacterium Tuberculosis H37Rv and its Probable Role in Xenobiotic Degradation.Antimycobacterial and synergistic effects of 18β-glycyrrhetinic acid or glycyrrhetinic acid-30-piperazine in combination with isoniazid, rifampicin or streptomycin against Mycobacterium bovis.
P2860
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P2860
Functional role of the PE domain and immunogenicity of the Mycobacterium tuberculosis triacylglycerol hydrolase LipY.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Functional role of the PE doma ...... riacylglycerol hydrolase LipY.
@ast
Functional role of the PE doma ...... riacylglycerol hydrolase LipY.
@en
type
label
Functional role of the PE doma ...... riacylglycerol hydrolase LipY.
@ast
Functional role of the PE doma ...... riacylglycerol hydrolase LipY.
@en
prefLabel
Functional role of the PE doma ...... riacylglycerol hydrolase LipY.
@ast
Functional role of the PE doma ...... riacylglycerol hydrolase LipY.
@en
P2093
P2860
P50
P356
P1476
Functional role of the PE doma ...... riacylglycerol hydrolase LipY.
@en
P2093
Alistair K Brown
Beenu Joshi
Chantal de Chastellier
Kanhu C Mishra
Kithiganahalli N Balaji
Vishwa M Katoch
Yeddula Narayana
P2860
P304
P356
10.1128/IAI.00410-07
P407
P577
2007-10-15T00:00:00Z