A dilated cardiomyopathy mutation blunts adrenergic response and induces contractile dysfunction under chronic angiotensin II stress
about
Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca(2+)-sensitivity and suppress the modulation of Ca(2+)-sensitivity by troponin I phosphorylation.Abnormal contractility in human heart myofibrils from patients with dilated cardiomyopathy due to mutations in TTN and contractile protein genes.Molecular Defects in Cardiac Myofilament Ca2+-Regulation Due to Cardiomyopathy-Linked Mutations Can Be Reversed by Small Molecules Binding to Troponin.
P2860
A dilated cardiomyopathy mutation blunts adrenergic response and induces contractile dysfunction under chronic angiotensin II stress
description
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2015年の論文
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2015年学术文章
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name
A dilated cardiomyopathy mutat ...... chronic angiotensin II stress
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A dilated cardiomyopathy mutat ...... chronic angiotensin II stress
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type
label
A dilated cardiomyopathy mutat ...... chronic angiotensin II stress
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A dilated cardiomyopathy mutat ...... chronic angiotensin II stress
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prefLabel
A dilated cardiomyopathy mutat ...... chronic angiotensin II stress
@ast
A dilated cardiomyopathy mutat ...... chronic angiotensin II stress
@en
P2093
P2860
P1476
A dilated cardiomyopathy mutat ...... chronic angiotensin II stress
@en
P2093
Natalia Smoktunowicz
Ross Wilkinson
Weihua Song
P2860
P304
P356
10.1152/AJPHEART.00327.2015
P577
2015-10-02T00:00:00Z