Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunit
about
Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1HIV-1 Nef disrupts intracellular trafficking of major histocompatibility complex class I, CD4, CD8, and CD28 by distinct pathways that share common elementsRemodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceStructural basis of evasion of cellular adaptive immunity by HIV-1 NefOverlapping effector interfaces define the multiple functions of the HIV-1 Nef polyproline helix.Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functionsHIV-1 Nef targets MHC-I and CD4 for degradation via a final common beta-COP-dependent pathway in T cells.An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex.Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 NefSmall molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef actionRequirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in virus release.HIV-1 Nef binds a subpopulation of MHC-I throughout its trafficking itinerary and down-regulates MHC-I by perturbing both anterograde and retrograde trafficking.Self-association of the Lentivirus protein, NefTrans-cellular introduction of HIV-1 protein Nef induces pathogenic response in Caenorhabditis elegans.Nef neutralizes the ability of exosomes from CD4+ T cells to act as decoys during HIV-1 infection.At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis.Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.ADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1-infected primary T cells.A noncanonical mu-1A-binding motif in the N terminus of HIV-1 Nef determines its ability to downregulate major histocompatibility complex class I in T lymphocytesAn interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I.Human leukocyte antigen (HLA) class I down-regulation by human immunodeficiency virus type 1 negative factor (HIV-1 Nef): what might we learn from natural sequence variants?Improving HIV proteome annotation: new features of BioAfrica HIV Proteomics Resource.Functional characterization of the human immunodeficiency virus type 1 Nef acidic domain.HIV-1 Nef: at the crossroadsA basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.Mechanisms of HIV-1 Nef function and intracellular signaling.HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanismHLA-C as a mediator of natural killer and T-cell activation: spectator or key player?HIV immune evasion disruption of antigen presentation by the HIV Nef protein.The natural killer cell cytotoxic function is modulated by HIV-1 accessory proteins.The activity of Nef on HIV-1 infectivityModeling the evolution of SIV sooty mangabey progenitor virus towards HIV-2 using humanized mice.HIV-1 Nef: Taking Control of Protein Trafficking.Intracellular recycling and cross-presentation by MHC class I molecules.Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease.The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4+ T cells.
P2860
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P2860
Cooperative binding of the class I major histocompatibility complex cytoplasmic domain and human immunodeficiency virus type 1 Nef to the endosomal AP-1 complex via its mu subunit
description
2007 nî lūn-bûn
@nan
2007年の論文
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2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
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2007年學術文章
@zh-hant
name
Cooperative binding of the cla ...... P-1 complex via its mu subunit
@ast
Cooperative binding of the cla ...... P-1 complex via its mu subunit
@en
type
label
Cooperative binding of the cla ...... P-1 complex via its mu subunit
@ast
Cooperative binding of the cla ...... P-1 complex via its mu subunit
@en
prefLabel
Cooperative binding of the cla ...... P-1 complex via its mu subunit
@ast
Cooperative binding of the cla ...... P-1 complex via its mu subunit
@en
P2860
P356
P1433
P1476
Cooperative binding of the cla ...... P-1 complex via its mu subunit
@en
P2093
Colleen M Noviello
John C Guatelli
P2860
P304
P356
10.1128/JVI.00660-07
P407
P577
2007-12-05T00:00:00Z