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Ubiquitin-Mediated Degradation of Aurora KinasesFunctional Significance of Aurora Kinases-p53 Protein Family Interactions in CancerAurora kinases: novel therapy targets in cancersThe negative interplay between Aurora A/B and BRCA1/2 controls cancer cell growth and tumorigenesis via distinct regulation of cell cycle progression, cytokinesis, and tetraploidyCircadian Clock Gene CRY2 Degradation Is Involved in Chemoresistance of Colorectal Cancer.Genomic profiling of patient-derived colon cancer xenograft modelsDependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint.Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsAurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1).RACK1 to the future--a historical perspectiveFBW7-Aurora B-p53 feedback loop regulates mitosis and cell growth.VRK1 and AURKB form a complex that cross inhibit their kinase activity and the phosphorylation of histone H3 in the progression of mitosis.FBW7 is associated with prognosis, inhibits malignancies and enhances temozolomide sensitivity in glioblastoma cells.Next-Generation Sequencing.Haploid genetic screens identify genetic vulnerabilities to microtubule-targeting agents.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
FBXW7 is involved in Aurora B degradation.
@ast
FBXW7 is involved in Aurora B degradation.
@en
type
label
FBXW7 is involved in Aurora B degradation.
@ast
FBXW7 is involved in Aurora B degradation.
@en
prefLabel
FBXW7 is involved in Aurora B degradation.
@ast
FBXW7 is involved in Aurora B degradation.
@en
P2093
P2860
P356
P1433
P1476
FBXW7 is involved in Aurora B degradation
@en
P2093
Chieh-Lin Teng
Chris Gully
Guermarie Velazquez-Torres
Jihyun Shin
Sai-Ching J Yeung
Shih-Lan Hsu
Stephen Skerl
Yun-Chi Hsieh
P2860
P304
P356
10.4161/CC.22381
P577
2012-10-24T00:00:00Z