HSP90: a rising star on the horizon of anticancer targets. - Wikidata - awgldk - TriplyDB

HSP90: a rising star on the horizon of anticancer targets.

HSP90: a rising star on the horizon of anticancer targets.

http://www.wikidata.org/entity/Q36429542

about

Autophagy and NF-kappaB: fight for fate High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888 Hsp90 inhibitors block outgrowth of EBV-infected malignant cells in vitro and in vivo through an EBNA1-dependent mechanism.Geldanamycin and Its Derivatives Inhibit the Growth of Myeloma Cells and Reduce the Expression of the MET Receptor.Evolutionary constraints on chaperone-mediated folding provide an antiviral approach refractory to development of drug resistance.Proteotoxic stress of cancer: implication of the heat-shock response in oncogenesis.Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cells New developments in Hsp90 inhibitors as anti-cancer therapeutics: mechanisms, clinical perspective and more potential.Apoptosis versus cell differentiation: role of heat shock proteins HSP90, HSP70 and HSP27 Targeting malignant mitochondria with therapeutic peptides.Synthesis and biological evaluation of coumarin replacements of novobiocin as Hsp90 inhibitors.Akt shows variable sensitivity to an Hsp90 inhibitor depending on cell context.

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HSP90: a rising star on the horizon of anticancer targets.

http://www.wikidata.org/entity/Q36429542

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2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年學術文章

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HSP90: a rising star on the horizon of anticancer targets.

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HSP90: a rising star on the horizon of anticancer targets.

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HSP90: a rising star on the horizon of anticancer targets.

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HSP90: a rising star on the horizon of anticancer targets.

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HSP90: a rising star on the horizon of anticancer targets.

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HSP90: a rising star on the horizon of anticancer targets.

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Future Oncology

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HSP90: a rising star on the horizon of anticancer targets.

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P2860

Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation.

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains

Modulation of Akt kinase activity by binding to Hsp90

Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions

A molecular clamp in the crystal structure of the N-terminal domain of the yeast Hsp90 chaperone

Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone

ErbB2 degradation mediated by the co-chaperone protein CHIP

Functional proteomic screens reveal an essential extracellular role for hsp90 alpha in cancer cell invasiveness

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