Cowden syndrome-affected patients with PTEN promoter mutations demonstrate abnormal protein translation.
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A comprehensive functional analysis of PTEN mutations: implications in tumor- and autism-related syndromesA clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probandsCutaneous manifestation of gastrointestinal diseaseDiverse mechanisms of AKT pathway activation in human malignancyHereditary Syndromes Manifesting as Endometrial Carcinoma: How Can Pathological Features Aid Risk Assessment?RNAsnp: efficient detection of local RNA secondary structure changes induced by SNPs.Germline alterations in RASAL1 in Cowden syndrome patients presenting with follicular thyroid cancer and in individuals with apparently sporadic epithelial thyroid cancerSecond malignant neoplasms in patients with Cowden syndrome with underlying germline PTEN mutations.MicroRNA-22 suppresses the growth, migration and invasion of colorectal cancer cells through a Sp1 negative feedback loop.Clinical management of hereditary breast cancer syndromes.Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant.Germline PTEN, SDHB-D, and KLLN alterations in endometrial cancer patients with Cowden and Cowden-like syndromes: an international, multicenter, prospective studyIncidence and clinical characteristics of thyroid cancer in prospective series of individuals with Cowden and Cowden-like syndrome characterized by germline PTEN, SDH, or KLLN alterationsLifetime cancer risks in individuals with germline PTEN mutations.Structural effects of linkage disequilibrium on the transcriptome.Variants on the promoter region of PTEN affect breast cancer progression and patient survival.The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia.Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypesDifferential expression of PTEN-targeting microRNAs miR-19a and miR-21 in Cowden syndromeA recessive form of extreme macrocephaly and mild intellectual disability complements the spectrum of PTEN hamartoma tumour syndromeGermline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome.A novel PTEN gene promoter mutation and untypical Cowden syndrome.Protein tyrosine phosphatases: dual-specificity phosphatases in health and disease.Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genesPeripheral thyrotropin receptor mRNA as a novel marker for differentiated thyroid cancer diagnosis and surveillance.Exome sequencing reveals germline gain-of-function EGFR mutation in an adult with Lhermitte-Duclos disease.Immune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells.Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps.Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers.Transcriptome-wide analysis of UTRs in non-small cell lung cancer reveals cancer-related genes with SNV-induced changes on RNA secondary structure and miRNA target sites.Germline TTN variants are enriched in PTEN-wildtype Bannayan-Riley-Ruvalcaba syndrome.PTENHamartoma Tumor Syndrome
P2860
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P2860
Cowden syndrome-affected patients with PTEN promoter mutations demonstrate abnormal protein translation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Cowden syndrome-affected patie ...... abnormal protein translation.
@ast
Cowden syndrome-affected patie ...... abnormal protein translation.
@en
type
label
Cowden syndrome-affected patie ...... abnormal protein translation.
@ast
Cowden syndrome-affected patie ...... abnormal protein translation.
@en
prefLabel
Cowden syndrome-affected patie ...... abnormal protein translation.
@ast
Cowden syndrome-affected patie ...... abnormal protein translation.
@en
P2093
P2860
P356
P1476
Cowden syndrome-affected patie ...... abnormal protein translation.
@en
P2093
Charis Eng
Kevin M Zbuk
Kristin A Waite
Marcus G Pezzolesi
Rosemary E Teresi
P2860
P304
P356
10.1086/521051
P407
P577
2007-08-15T00:00:00Z