Allosteric gating of a large conductance Ca-activated K+ channel.
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The beta subunit increases the Ca2+ sensitivity of large conductance Ca2+-activated potassium channels by retaining the gating in the bursting statesGating mechanism of BK (Slo1) channels: so near, yet so farInactivation of BK channels mediated by the NH(2) terminus of the beta3b auxiliary subunit involves a two-step mechanism: possible separation of binding and blockadeGating properties conferred on BK channels by the beta3b auxiliary subunit in the absence of its NH(2)- and COOH terminiSlo3 K+ channels: voltage and pH dependence of macroscopic currentspH-regulated Slo3 K+ channels: properties of unitary currentsStructural determinants for functional coupling between the beta and alpha subunits in the Ca2+-activated K+ (BK) channelFunctional implications of axon initial segment cytoskeletal disruption in strokeBK channels: multiple sensors, one activation gateNMR structure of the "ball-and-chain" domain of KCNMB2, the beta 2-subunit of large conductance Ca2+- and voltage-activated potassium channelsRole of the S4 segment in a voltage-dependent calcium-sensitive potassium (hSlo) channelUrodynamic properties and neurotransmitter dependence of urinary bladder contractility in the BK channel deletion model of overactive bladderFunctional effects of auxiliary beta4-subunit on rat large-conductance Ca(2+)-activated K(+) channelSteady-state and closed-state inactivation properties of inactivating BK channelsDefinition of two agonist types at the mammalian cold-activated channel TRPM8A quantized mechanism for activation of pannexin channelsPersistence and storage of activity patterns in spiking recurrent cortical networks: modulation of sigmoid signals by after-hyperpolarization currents and acetylcholine.A linkage analysis toolkit for studying allosteric networks in ion channels.Voltage dependence of the coupling of Ca(2+) sparks to BK(Ca) channels in urinary bladder smooth muscle.RACK1 is a BKCa channel binding protein.Alpha5beta1 integrin engagement increases large conductance, Ca2+-activated K+ channel current and Ca2+ sensitivity through c-src-mediated channel phosphorylation.A BK (Slo1) channel journey from molecule to physiology.Location of modulatory beta subunits in BK potassium channels.Coupling and cooperativity in voltage activation of a limited-state BK channel gating in saturating Ca2+.Relationships between structural dynamics and functional kinetics in oligomeric membrane receptorsAn epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing.Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+.BK channel activation: structural and functional insightsCa2+-dependent gating mechanisms for dSlo, a large-conductance Ca2+-activated K+ (BK) channel.Complex voltage-dependent behavior of single unliganded calcium-sensitive potassium channels.Modeling hair cell tuning by expression gradients of potassium channel beta subunits.Capsaicin activation of the pain receptor, VR1: multiple open states from both partial and full binding.Optimal estimation of ion-channel kinetics from macroscopic currents.Ion sensing in the RCK1 domain of BK channels.A quantitative model of human jejunal smooth muscle cell electrophysiology.Interfacial gating triad is crucial for electromechanical transduction in voltage-activated potassium channels.BK channels regulate sinoatrial node firing rate and cardiac pacing in vivoVoltage- and cold-dependent gating of single TRPM8 ion channels.Enhancement effects of martentoxin on glioma BK channel and BK channel (α+β1) subtypes.Temperature and voltage coupling to channel opening in transient receptor potential melastatin 8 (TRPM8).
P2860
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P2860
Allosteric gating of a large conductance Ca-activated K+ channel.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Allosteric gating of a large conductance Ca-activated K+ channel.
@ast
Allosteric gating of a large conductance Ca-activated K+ channel.
@en
type
label
Allosteric gating of a large conductance Ca-activated K+ channel.
@ast
Allosteric gating of a large conductance Ca-activated K+ channel.
@en
prefLabel
Allosteric gating of a large conductance Ca-activated K+ channel.
@ast
Allosteric gating of a large conductance Ca-activated K+ channel.
@en
P2093
P2860
P356
P1476
Allosteric gating of a large conductance Ca-activated K+ channel.
@en
P2093
P2860
P304
P356
10.1085/JGP.110.3.257
P577
1997-09-01T00:00:00Z