The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia.
about
The involvement of Reelin in neurodevelopmental disorders.Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylationEpigenetic mechanisms in schizophreniaThe reelin and GAD67 promoters are activated by epigenetic drugs that facilitate the disruption of local repressor complexesEpigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorderHistone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promotersStructural Insights into Reelin Function: Present and FutureEpigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric DisordersSchizophrenia and reelin: a model based on prenatal stress to study epigenetics, brain development and behaviorEpigenetic mechanisms in experience-driven memory formation and behaviorRAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expressionPrenatal stress down-regulates Reelin expression by methylation of its promoter and induces adult behavioral impairments in ratsEpigenetic regulation of the stem cell mitogen Fgf-2 by Mbd1 in adult neural stem/progenitor cellsEpigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice.Reelin supplementation recovers sensorimotor gating, synaptic plasticity and associative learning deficits in the heterozygous reeler mouse.Selective epigenetic alteration of layer I GABAergic neurons isolated from prefrontal cortex of schizophrenia patients using laser-assisted microdissection.Pharmacology of epigenetics in brain disordersAltered Organization of GABA(A) Receptor mRNA Expression in the Depressed Suicide BrainThe genetic variation of RELN expression in schizophrenia and bipolar disorder.Epigenetic GABAergic targets in schizophrenia and bipolar disorder.Reelin is involved in transforming growth factor-β1-induced cell migration in esophageal carcinoma cells.Loss of reelin expression in breast cancer is epigenetically controlled and associated with poor prognosisAn upregulation of DNA-methyltransferase 1 and 3a expressed in telencephalic GABAergic neurons of schizophrenia patients is also detected in peripheral blood lymphocytes.Neurodevelopment, GABA system dysfunction, and schizophreniaPersonalized medicine in psychiatry: problems and promises.Gene expression profiling in rodent models for schizophrenia.Increased reelin promoter methylation is associated with granule cell dispersion in human temporal lobe epilepsy.How does the social environment 'get into the mind'? Epigenetics at the intersection of social and psychiatric epidemiology.Increased Blood-Reelin-Levels in First Episode SchizophreniaEzh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex.The dynamics of DNA methylation in schizophrenia and related psychiatric disorders.DNA methylation and its implications and accessibility for neuropsychiatric therapeutics.Decreased cortical muscarinic M1 receptors in schizophrenia are associated with changes in gene promoter methylation, mRNA and gene targeting microRNA.GABA(A) receptor downregulation in brains of subjects with autism.DNA methyltransferases1 (DNMT1) and 3a (DNMT3a) colocalize with GAD67-positive neurons in the GAD67-GFP mouse brain.Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?How the epigenome contributes to the development of psychiatric disorders.A neurochemical basis for an epigenetic vision of psychiatric disorders (1994-2009).Epigenetics of psychoactive drugs.Reelin signaling in development, maintenance, and plasticity of neural networks
P2860
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P2860
The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
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2006年學術文章
@zh-hant
name
The human reelin gene: transcr ...... switch (+/-) in schizophrenia.
@ast
The human reelin gene: transcr ...... switch (+/-) in schizophrenia.
@en
type
label
The human reelin gene: transcr ...... switch (+/-) in schizophrenia.
@ast
The human reelin gene: transcr ...... switch (+/-) in schizophrenia.
@en
prefLabel
The human reelin gene: transcr ...... switch (+/-) in schizophrenia.
@ast
The human reelin gene: transcr ...... switch (+/-) in schizophrenia.
@en
P2093
P1476
The human reelin gene: transcr ...... switch (+/-) in schizophrenia
@en
P2093
Alessandro Guidotti
Dennis R Grayson
Erminio Costa
Rajiv P Sharma
P304
P356
10.1016/J.PHARMTHERA.2005.01.007
P577
2006-03-30T00:00:00Z