Heparanase enhances the insulin receptor signaling pathway to activate extracellular signal-regulated kinase in multiple myeloma.
about
Oncosuppressive functions of decorinInvolvement of heparanase in atherosclerosis and other vessel wall pathologiesMechanisms of heparanase inhibitors in cancer therapy.Versatile role of heparanase in inflammationHeparanase enhances myeloma progression via CXCL10 downregulation.Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylationHigh glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression.Heparanase induced by advanced glycation end products (AGEs) promotes macrophage migration involving RAGE and PI3K/AKT pathwayProteoglycans and their roles in brain cancer.Dichotomy of decorin activity on the insulin-like growth factor-I systemHeparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cellsHuman telomerase reverse transcriptase (hTERT) promotes gastric cancer invasion through cooperating with c-Myc to upregulate heparanase expressionSerglycin proteoglycan is required for multiple myeloma cell adhesion, in vivo growth, and vascularization.Heparanase augments insulin receptor signaling in breast carcinoma.The heparanase/syndecan-1 axis in cancer: mechanisms and therapies.Heparanase in inflammation and inflammation-associated cancer.RNA interference for multiple myeloma therapy: targeting signal transduction pathways.Heparanase: a rainbow pharmacological target associated to multiple pathologies including rare diseases.Insights into the molecular roles of heparan sulfate proteoglycans (HSPGs-syndecans) in autocrine and paracrine growth factor signaling in the pathogenesis of Hodgkin's lymphoma.Bruton's tyrosine kinase: potential target in human multiple myeloma.PI-88 inhibits postoperative recurrence of hepatocellular carcinoma via disrupting the surge of heparanase after liver resection.Heparan Sulfate Glycosaminoglycans in Glioblastoma Promote Tumor Invasion.High glucose facilitated endothelial heparanase transfer to the cardiomyocyte modifies its cell death signature.Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior.Identification of key genes and pathways in uterine leiomyosarcoma through bioinformatics analysis.
P2860
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P2860
Heparanase enhances the insulin receptor signaling pathway to activate extracellular signal-regulated kinase in multiple myeloma.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-my
2012年学术文章
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2012年學術文章
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2012年學術文章
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2012年學術文章
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name
Heparanase enhances the insuli ...... ed kinase in multiple myeloma.
@ast
Heparanase enhances the insuli ...... ed kinase in multiple myeloma.
@en
type
label
Heparanase enhances the insuli ...... ed kinase in multiple myeloma.
@ast
Heparanase enhances the insuli ...... ed kinase in multiple myeloma.
@en
prefLabel
Heparanase enhances the insuli ...... ed kinase in multiple myeloma.
@ast
Heparanase enhances the insuli ...... ed kinase in multiple myeloma.
@en
P2093
P2860
P356
P1476
Heparanase enhances the insuli ...... ed kinase in multiple myeloma.
@en
P2093
Anurag Purushothaman
Ralph D Sanderson
Stephen K Babitz
P2860
P304
41288-41296
P356
10.1074/JBC.M112.391417
P407
P577
2012-10-09T00:00:00Z