In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors.
about
An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamicsFructose modulates GLUT5 mRNA stability in differentiated Caco-2 cells: role of cAMP-signalling pathway and PABP (polyadenylated-binding protein)-interacting protein (Paip) 2The many dimensions of cAMP signalingAKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complexLight modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium BeggiatoaMolecular details of cAMP generation in mammalian cells: a tale of two systemsRoles of cyclic diguanylate in the regulation of bacterial pathogenesisEndoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expressionGenetically-encoded tools for cAMP probing and modulation in living systemsThe genetically encoded tool set for investigating cAMP: more than the sum of its partsStudying GPCR/cAMP pharmacology from the perspective of cellular structureThe role of type 4 phosphodiesterases in generating microdomains of cAMP: large scale stochastic simulationsAnatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders.Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay.A uniform extracellular stimulus triggers distinct cAMP signals in different compartments of a simple cellHigh density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor.β-Adrenergic cAMP signals are predominantly regulated by phosphodiesterase type 4 in cultured adult rat aortic smooth muscle cellsRegulation and organization of adenylyl cyclases and cAMP.PDE4D and PDE4B function in distinct subcellular compartments in mouse embryonic fibroblastsAlteration of vascular reactivity in heart failure: role of phosphodiesterases 3 and 4.Pseudomonas aeruginosa exotoxin Y-mediated tau hyperphosphorylation impairs microtubule assembly in pulmonary microvascular endothelial cells.PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalizationA2B adenosine receptors inhibit superoxide production from mitochondrial complex I in rabbit cardiomyocytes via a mechanism sensitive to Pertussis toxinPDE4: arrested at the border.Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13.Compartmentation of cAMP signaling in cardiac myocytes: a computational study.Cyclic guanosine monophosphate compartmentation in rat cardiac myocytesEstimating the magnitude of near-membrane PDE4 activity in living cellsA specific pattern of phosphodiesterases controls the cAMP signals generated by different Gs-coupled receptors in adult rat ventricular myocytes.A-kinase anchoring proteins regulate compartmentalized cAMP signaling in airway smooth muscle.Natriuretic peptides and nitric oxide stimulate cGMP synthesis in different cellular compartments.Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.Monitoring of cAMP synthesis and degradation in living cells.Pseudechetoxin binds to the pore turret of cyclic nucleotide-gated ion channels.Cellular mechanisms underlying prostaglandin-induced transient cAMP signals near the plasma membrane of HEK-293 cells.A-kinase anchoring proteins take shape.All preconditioning-related G protein-coupled receptors can be demonstrated in the rabbit cardiomyocyte.Mechanisms Restricting Diffusion of Intracellular cAMP.Roles of GRK and PDE4 activities in the regulation of beta2 adrenergic signalingCa(2+) -stimulated basal adenylyl cyclase activity localization in membrane lipid microdomains of cardiac sinoatrial nodal pacemaker cells.
P2860
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P2860
In vivo assessment of local phosphodiesterase activity using tailored cyclic nucleotide-gated channels as cAMP sensors.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
In vivo assessment of local ph ...... ated channels as cAMP sensors.
@ast
In vivo assessment of local ph ...... ated channels as cAMP sensors.
@en
type
label
In vivo assessment of local ph ...... ated channels as cAMP sensors.
@ast
In vivo assessment of local ph ...... ated channels as cAMP sensors.
@en
prefLabel
In vivo assessment of local ph ...... ated channels as cAMP sensors.
@ast
In vivo assessment of local ph ...... ated channels as cAMP sensors.
@en
P2093
P2860
P356
P1476
In vivo assessment of local ph ...... ated channels as cAMP sensors.
@en
P2093
P2860
P356
10.1085/JGP.118.1.63
P577
2001-07-01T00:00:00Z