Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay.

Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay.

Item
http://www.wikidata.org/entity/Q30466708
Genetically-encoded tools for cAMP probing and modulation in living systemsOsthole: A Review on Its Bioactivities, Pharmacological Properties, and Potential as Alternative MedicineG-protein-coupled receptors targeting: the allosteric approachDevelopment of an assay for high-throughput energy expenditure monitoring in the zebrafishMelanocortin-3 receptors and metabolic homeostasis.MC4R expression in pedunculopontine nucleus involved in the modulation of midbrain dopamine system.A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo.hMRAPα, but Not hMRAP2, Enhances hMC4R Constitutive Activity in HEK293 Cells and This Is Not Dependent on hMRAPα Induced Changes in hMC4R Complex N-linked Glycosylation.Manipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestinsSET protein interacts with intracellular domains of the gonadotropin-releasing hormone receptor and differentially regulates receptor signaling to cAMP and calcium in gonadotrope cells.Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3Probing heterotrimeric G protein activation: applications to biased ligands.An update of novel screening methods for GPCR in drug discovery.A Duplexed High-Throughput Screen to Identify Allosteric Modulators of the Glucagon-Like Peptide 1 and Glucagon Receptors.Melanocortins, Melanocortin Receptors and Multiple Sclerosis.A real-time, fluorescence-based assay for measuring μ-opioid receptor modulation of adenylyl cyclase activity in Chinese hamster ovary cells.
P2860

Development of a high throughput screen for allosteric modulators of melanocortin-4 receptor signaling using a real time cAMP assay.

Item
http://www.wikidata.org/entity/Q30466708
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Development of a high throughp ...... using a real time cAMP assay.
@ast
Development of a high throughp ...... using a real time cAMP assay.
@en
type
label
Development of a high throughp ...... using a real time cAMP assay.
@ast
Development of a high throughp ...... using a real time cAMP assay.
@en
prefLabel
Development of a high throughp ...... using a real time cAMP assay.
@ast
Development of a high throughp ...... using a real time cAMP assay.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
Development of a high throughp ...... using a real time cAMP assay.
@en
P2093
P2860
P304
P31
P356
10.1016/J.EJPHAR.2011.01.031
P407
P433
P478
P50
P577
P5875
P698
P921
P932