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Pushing tumor cells towards a malignant phenotype: stimuli from the microenvironment, intercellular communications and alternative roadsAutophagy and regulation of cilia function and assemblyHCV derived from sera of HCV-infected patients induces pro-fibrotic effects in human primary fibroblasts by activating GLI2The Cilium: Cellular Antenna and Central Processing UnitAutophagy in thyroid cancer: present knowledge and future perspectivesCapsaicin triggers autophagic cell survival which drives epithelial mesenchymal transition and chemoresistance in bladder cancer cells in an Hedgehog-dependent mannerFunctional interaction between autophagy and ciliogenesisCholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epitheliumSelective inhibition of IFNG-induced autophagy by Mir155- and Mir31-responsive WNT5A and SHH signalingPhylogenetic analyses and characterization of RNase X25 from Drosophila melanogaster suggest a conserved housekeeping role and additional functions for RNase T2 enzymes in protostomes.Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.Cyclopamine modulates γ-secretase-mediated cleavage of amyloid precursor protein by altering its subcellular trafficking and lysosomal degradationInhibition of autophagy potentiates the efficacy of Gli inhibitor GANT-61 in MYCN-amplified neuroblastoma cellsTargeting Hedgehog signaling pathway and autophagy overcomes drug resistance of BCR-ABL-positive chronic myeloid leukemiaReciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways.Autophagy and primary cilia: dual interplaySonic hedgehog promotes autophagy in hippocampal neurons.Myc inhibition impairs autophagosome formation.Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells.Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis.Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway.Gli1 inhibition suppressed cell growth and cell cycle progression and induced apoptosis as well as autophagy depending on ERK1/2 activity in human chondrosarcoma cells.Hedgehog Inhibitors in Rhabdomyosarcoma: A Comparison of Four Compounds and Responsiveness of Four Cell Lines.Atg1-independent induction of autophagy by the Drosophila Ulk3 homolog, ADUK.Shh-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh signalling.Autophagy maintains the stemness of ovarian cancer stem cells by FOXA2.Autophagic Flux is Regulated by Interaction Between the C-terminal Domain of Patched1 and ATG101.Nutrient sensing, growth and senescence.Digesting cytotoxic stressors - an unconventional mechanism to induce autophagy.The protective autophagy activated by GANT-61 in MYCN amplified neuroblastoma cells is mediated by PERK.How Tumor Cells Choose Between Epithelial-Mesenchymal Transition and Autophagy to Resist Stress-Therapeutic Implications.Emerging Roles of Sonic Hedgehog in Adult Neurological Diseases: Neurogenesis and BeyondHedgehog Signaling Pathway and Autophagy in Cancer
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The Hedgehog signalling pathway regulates autophagy.
@ast
The Hedgehog signalling pathway regulates autophagy.
@en
type
label
The Hedgehog signalling pathway regulates autophagy.
@ast
The Hedgehog signalling pathway regulates autophagy.
@en
prefLabel
The Hedgehog signalling pathway regulates autophagy.
@ast
The Hedgehog signalling pathway regulates autophagy.
@en
P2093
P2860
P356
P1476
The Hedgehog signalling pathway regulates autophagy
@en
P2093
David C Rubinsztein
Fiona M Menzies
Nikol Simecek
Thomas P Neufeld
Yu-Yun Chang
P2860
P2888
P356
10.1038/NCOMMS2212
P407
P577
2012-01-01T00:00:00Z