Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
about
Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchangerStructure of a eukaryotic CLC transporter defines an intermediate state in the transport cycleMolecular mechanism of proton transport in CLC Cl-/H+ exchange transporters13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1.A cytoplasmic domain mutation in ClC-Kb affects long-distance communication across the membraneEvaluation of the membrane-spanning domain of ClC-2Accessibility of the CLC-0 pore to charged methanethiosulfonate reagents.Antiport mechanism for Cl(-)/H(+) in ClC-ec1 from normal-mode analysis.Chloride channels: often enigmatic, rarely predictable.Dual roles of the sixth transmembrane segment of the CFTR chloride channel in gating and permeation.Ion-binding properties of the ClC chloride selectivity filter.Side-dependent inhibition of a prokaryotic ClC by DIDS.Carboxy terminus splice variation alters ClC channel gating and extracellular cysteine reactivityRoles of K149, G352, and H401 in the channel functions of ClC-0: testing the predictions from theoretical calculations.The role of a conserved lysine in chloride- and voltage-dependent ClC-0 fast gatingThe mechanism of fast-gate opening in ClC-0.CLC anion channel regulatory phosphorylation and conserved signal transduction domainsClC chloride channels viewed through a transporter lens.A designed inhibitor of a CLC antiporter blocks function through a unique binding mode.Computationally Efficient Multiscale Reactive Molecular Dynamics to Describe Amino Acid Deprotonation in Proteins.Cysteine scanning of CFTR's first transmembrane segment reveals its plausible roles in gating and permeationCLC Cl /H+ transporters constrained by covalent cross-linking.Intracellular proton regulation of ClC-0The CLC 'chloride channel' family: revelations from prokaryotes.The ClC-0 chloride channel is a 'broken' Cl-/H+ antiporterInsights into the ClC-4 transport mechanism from studies of Zn2+ inhibitionCLC-0 and CFTR: chloride channels evolved from transporters.Review. Proton-coupled gating in chloride channelsA single point mutation reveals gating of the human ClC-5 Cl-/H+ antiporter.Ion channels versus ion pumps: the principal difference, in principle.Water access points and hydration pathways in CLC H+/Cl- transporters.A tale of two CLCs: biophysical insights toward understanding ClC-5 and ClC-7 function in endosomes and lysosomes.Helix O modulates voltage dependency of CLC-1.Unique gating properties of C. elegans ClC anion channel splice variants are determined by altered CBS domain conformation and the R-helix linker.Putting the pieces together: a crystal clear window into CLC anion channel regulationChannel-like slippage modes in the human anion/proton exchanger ClC-4.Extracellular determinants of anion discrimination of the Cl-/H+ antiporter protein CLC-5.Chloride Ion Transport by the E. coli CLC Cl-/H+ Antiporter: A Combined Quantum-Mechanical and Molecular-Mechanical Study.CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and PhysiologyMolecular determinants of common gating of a ClC chloride channel
P2860
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P2860
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
@ast
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
@en
type
label
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
@ast
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
@en
prefLabel
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
@ast
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
@en
P2860
P356
P1476
Cysteine accessibility in ClC-0 supports conservation of the ClC intracellular vestibule
@en
P2093
Anita M Engh
Merritt Maduke
P2860
P304
P356
10.1085/JGP.200509258
P577
2005-05-16T00:00:00Z