Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes - Wikidata - awgldk - TriplyDB

Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes

Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes

http://www.wikidata.org/entity/Q36447819

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NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomes Cullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic Implications Epigenetic modulators, modifiers and mediators in cancer aetiology and progression Chromodomain helicase DNA-binding proteins in stem cells and human developmental diseases The estrogen receptor joins other cancer biomarkers as a predictor of outcome Genomic landscape of human papillomavirus-associated cancers SWI/SNF chromatin remodeling complexes and cancer New concepts for an old problem: the diagnosis of endometrial hyperplasia Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer The mutational landscape of endometrial cancer Dysregulation of ubiquitin ligases in cancer SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2 Integrated genomic characterization of endometrial carcinoma The SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseases Inactivating CUX1 mutations promote tumorigenesis An evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic development MBD3 localizes at promoters, gene bodies and enhancers of active genes De Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive Dysmorphisms Idiopathic Inflammatory Myopathies and Malignancy: a Comprehensive Review.Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.ChromoHub V2: cancer genomics.The mutational landscape of chromatin regulatory factors across 4,623 tumor samples.Inferring pathway dysregulation in cancers from multiple types of omic data.Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer Data on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations.Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer.Mutations of Chromatin Structure Regulating Genes in Human Malignancies.Differential expression and sex chromosome association of CHD3/4 and CHD5 during spermatogenesis Epithelial-to-Mesenchymal Transition in the Female Reproductive Tract: From Normal Functioning to Disease Pathology.Chromatin-regulating proteins as targets for cancer therapy.Novel genetic targets in endometrial cancer.The emerging genomic landscape of endometrial cancer.Landscape of genomic alterations in cervical carcinomas.Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.The promise of whole-exome sequencing in medical genetics.The emerging role of speckle-type POZ protein (SPOP) in cancer development.Architects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromes Prostate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer.

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Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes

http://www.wikidata.org/entity/Q36447819

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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name

Exome sequencing of serous end ...... ubiquitin ligase complex genes

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Exome sequencing of serous end ...... ubiquitin ligase complex genes

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type

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Exome sequencing of serous end ...... ubiquitin ligase complex genes

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Exome sequencing of serous end ...... ubiquitin ligase complex genes

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prefLabel

Exome sequencing of serous end ...... ubiquitin ligase complex genes

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Exome sequencing of serous end ...... ubiquitin ligase complex genes

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P1433

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Nature Genetics

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Exome sequencing of serous end ...... ubiquitin ligase complex genes

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P2093

Andrea J O'Hara

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Andrew K Godwin

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Bryant M England

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Daphne W Bell

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Dennis C Sgroi

http://www.w3.org/2001/XMLSchema#string

Jessica C Price

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Maria J Merino

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Mary Ellen Urick

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Meghan L Rudd

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NIH Intramural Sequencing Center (NISC) Comparative Sequencing Program

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P2860

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

ARID1A mutations in endometriosis-associated ovarian carcinomas

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer

The Catalogue of Somatic Mutations in Cancer (COSMIC)

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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1310-1315

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scholarly article

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10.1038/NG.2455

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12

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44

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Matthieu Le Gallo

James C Mullikin

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2012-10-28T00:00:00Z

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232720495

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3515204

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