Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes
about
NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomesCullin 3 Ubiquitin Ligases in Cancer Biology: Functions and Therapeutic ImplicationsEpigenetic modulators, modifiers and mediators in cancer aetiology and progressionChromodomain helicase DNA-binding proteins in stem cells and human developmental diseasesThe estrogen receptor joins other cancer biomarkers as a predictor of outcomeGenomic landscape of human papillomavirus-associated cancersSWI/SNF chromatin remodeling complexes and cancerNew concepts for an old problem: the diagnosis of endometrial hyperplasiaAcetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and CancerThe mutational landscape of endometrial cancerDysregulation of ubiquitin ligases in cancerSWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2Integrated genomic characterization of endometrial carcinomaThe SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseasesInactivating CUX1 mutations promote tumorigenesisAn evolutionarily conserved synthetic lethal interaction network identifies FEN1 as a broad-spectrum target for anticancer therapeutic developmentMBD3 localizes at promoters, gene bodies and enhancers of active genesDe Novo Mutations in CHD4, an ATP-Dependent Chromatin Remodeler Gene, Cause an Intellectual Disability Syndrome with Distinctive DysmorphismsIdiopathic Inflammatory Myopathies and Malignancy: a Comprehensive Review.Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.ChromoHub V2: cancer genomics.The mutational landscape of chromatin regulatory factors across 4,623 tumor samples.Inferring pathway dysregulation in cancers from multiple types of omic data.Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancerData on affected cancer-related genes in pediatric t(12;21)-positive acute lymphoblastic leukemia patients harboring unbalanced der(6)t(X;6) translocations.Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.Genome-wide analysis of gynecologic cancer: The Cancer Genome Atlas in ovarian and endometrial cancer.Mutations of Chromatin Structure Regulating Genes in Human Malignancies.Differential expression and sex chromosome association of CHD3/4 and CHD5 during spermatogenesisEpithelial-to-Mesenchymal Transition in the Female Reproductive Tract: From Normal Functioning to Disease Pathology.Chromatin-regulating proteins as targets for cancer therapy.Novel genetic targets in endometrial cancer.The emerging genomic landscape of endometrial cancer.Landscape of genomic alterations in cervical carcinomas.Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.Ovarian and endometrial endometrioid carcinomas have distinct CTNNB1 and PTEN mutation profiles.The promise of whole-exome sequencing in medical genetics.The emerging role of speckle-type POZ protein (SPOP) in cancer development.Architects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromesProstate cancer. Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer.
P2860
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P2860
Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Exome sequencing of serous end ...... ubiquitin ligase complex genes
@ast
Exome sequencing of serous end ...... ubiquitin ligase complex genes
@en
type
label
Exome sequencing of serous end ...... ubiquitin ligase complex genes
@ast
Exome sequencing of serous end ...... ubiquitin ligase complex genes
@en
prefLabel
Exome sequencing of serous end ...... ubiquitin ligase complex genes
@ast
Exome sequencing of serous end ...... ubiquitin ligase complex genes
@en
P2093
P2860
P50
P356
P1433
P1476
Exome sequencing of serous end ...... ubiquitin ligase complex genes
@en
P2093
Andrea J O'Hara
Andrew K Godwin
Bryant M England
Daphne W Bell
Dennis C Sgroi
Jessica C Price
Maria J Merino
Mary Ellen Urick
Meghan L Rudd
NIH Intramural Sequencing Center (NISC) Comparative Sequencing Program
P2860
P2888
P304
P356
10.1038/NG.2455
P407
P577
2012-10-28T00:00:00Z