Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. - Wikidata - awgldk - TriplyDB

Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum.

Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum.

http://www.wikidata.org/entity/Q36450321

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Mitophagy plays a central role in mitochondrial ageing Physiological and pathological implications of 5-hydroxymethylcytosine in diseases DNA Methylation: Insights into Human Evolution Decoding the non-coding genome: elucidating genetic risk outside the coding genome Enzymatic DNA oxidation: mechanisms and biological significance 5-Hydroxymethylcytosine: A new player in brain disorders?DNA methylation and healthy human aging Structural insights into how 5-hydroxymethylation influences transcription factor binding Effect of Hydroxymethylcytosine on the Structure and Stability of Holliday Junctions 5-Hydroxymethylcytosine: generation, fate, and genomic distribution Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntington's disease Epigenetic regulation in the inner ear and its potential roles in development, protection, and regeneration.Merging data from genetic and epigenetic approaches to better understand autistic spectrum disorder.Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA.High-throughput sequencing offers new insights into 5-hydroxymethylcytosine.Enrichment methods provide a feasible approach to comprehensive and adequately powered investigations of the brain methylome Cellular commitment in the developing cerebellum 5-Hydroxymethylcytosine: a stable or transient DNA modification?Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis.Friedreich ataxia patient tissues exhibit increased 5-hydroxymethylcytosine modification and decreased CTCF binding at the FXN locus Intermediate DNA methylation is a conserved signature of genome regulation.Effects of cytosine methylation on transcription factor binding sites Novel methylation markers of the dysexecutive-psychiatric phenotype in FMR1 premutation women.Hydroxymethylation of DNA: an epigenetic marker.Exploration of hydroxymethylation in Kagami-Ogata syndrome caused by hypermethylation of imprinting control regions.Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease.Altering 5-hydroxymethylcytosine modification impacts ischemic brain injury.Tet3 mediates stable glucocorticoid-induced alterations in DNA methylation and Dnmt3a/Dkk1 expression in neural progenitors.DNA methylation is critical for tooth agenesis: implications for sporadic non-syndromic anodontia and hypodontia.Reciprocal changes in DNA methylation and hydroxymethylation and a broad repressive epigenetic switch characterize FMR1 transcriptional silencing in fragile X syndrome C9orf72 promoter hypermethylation is reduced while hydroxymethylation is acquired during reprogramming of ALS patient cells.AF9 promotes hESC neural differentiation through recruiting TET2 to neurodevelopmental gene loci for methylcytosine hydroxylation.The landscape of DNA methylation amid a perfect storm of autism aetiologies.Early life adversity, genomic plasticity, and psychopathology.Epigenetic analysis of neurocognitive development at 1 year of age in a community-based pregnancy cohort.DNA methylation and differentiation: silencing, upregulation and modulation of gene expression.Epigenetics components of aging in the central nervous system.The emerging role of 5-hydroxymethylcytosine in neurodegenerative diseases.DIRECTION: A machine learning framework for predicting and characterizing DNA methylation and hydroxymethylation in mammalian genomes.Epigenetics studies of fetal alcohol spectrum disorder: where are we now?

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Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum.

http://www.wikidata.org/entity/Q36450321

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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Genome-wide DNA hydroxymethyla ...... e developing human cerebellum.

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Genome-wide DNA hydroxymethyla ...... e developing human cerebellum.

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type

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Genome-wide DNA hydroxymethyla ...... e developing human cerebellum.

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Genome-wide DNA hydroxymethyla ...... e developing human cerebellum.

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Genome-wide DNA hydroxymethyla ...... e developing human cerebellum.

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Genome-wide DNA hydroxymethyla ...... e developing human cerebellum.

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Human Molecular Genetics

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Genome-wide DNA hydroxymethyla ...... e developing human cerebellum.

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P2093

Chuan He

http://www.w3.org/2001/XMLSchema#string

Keith E Szulwach

http://www.w3.org/2001/XMLSchema#string

Li Lin

http://www.w3.org/2001/XMLSchema#string

Peng Jin

http://www.w3.org/2001/XMLSchema#string

Qian Pan

http://www.w3.org/2001/XMLSchema#string

Ranhui Duan

http://www.w3.org/2001/XMLSchema#string

Stephen T Warren

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Tao Wang

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Xuekun Li

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P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

Functional impact of global rare copy number variation in autism spectrum disorders

Distinct DNA methylation changes highly correlated with chronological age in the human brain

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5500-5510

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10.1093/HMG/DDS394

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26

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21

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232066479

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23042784

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3516134

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