A family of G protein βγ subunits translocate reversibly from the plasma membrane to endomembranes on receptor activation.
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Emerging roles for the FSH receptor adapter protein APPL1 and overlap of a putative 14-3-3τ interaction domain with a canonical G-protein interaction siteStructural determinants involved in the formation and activation of G protein betagamma dimers.Corticotropin releasing factor-induced CREB activation in striatal neurons occurs via a novel Gβγ signaling pathwayInhibition of G-protein βγ signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cellsGβ1γ2 activates phospholipase A2-dependent Golgi membrane tubule formationRACK1 regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC beta and PI3K gamma.Dynamic localization of G proteins in Dictyostelium discoideum.Optically triggering spatiotemporally confined GPCR activity in a cell and programming neurite initiation and extensionSubcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration.G protein subunit dissociation and translocation regulate cellular response to receptor stimulation.Regulation of G-protein signaling by RKTG via sequestration of the G betagamma subunit to the Golgi apparatusRegulation of Golgi structure and secretion by receptor-induced G protein βγ complex translocationA G-protein subunit translocation embedded network motif underlies GPCR regulation of calcium oscillationsShuttling and translocation of heterotrimeric G proteins and Ras.G protein βγ subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway.Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution.Polarity mediates asymmetric trafficking of the Gbeta heterotrimeric G-protein subunit GPB-1 in C. elegans embryosProtein Kinase D and Gβγ Subunits Mediate Agonist-evoked Translocation of Protease-activated Receptor-2 from the Golgi Apparatus to the Plasma Membrane.Shuttling of G protein subunits between the plasma membrane and intracellular membranes.G-protein signaling leverages subunit-dependent membrane affinity to differentially control βγ translocation to intracellular membranes.G protein-coupled receptor-promoted trafficking of Gbeta1gamma2 leads to AKT activation at endosomes via a mechanism mediated by Gbeta1gamma2-Rab11a interactionThe role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexesG protein βγ subunits: central mediators of G protein-coupled receptor signaling.Fluorescence changes reveal kinetic steps of muscarinic receptor-mediated modulation of phosphoinositides and Kv7.2/7.3 K+ channels.Submembraneous microtubule cytoskeleton: regulation of microtubule assembly by heterotrimeric Gproteins.Non-canonical signaling and localizations of heterotrimeric G proteins.G protein trafficking.Gβγ Pathways in Cell Polarity and Migration Linked to Oncogenic GPCR Signaling: Potential Relevance in Tumor Microenvironment.Central and C-terminal domains of heterotrimeric G protein gamma subunits differentially influence the signaling necessary for primordial germ cell migration.All G protein βγ complexes are capable of translocation on receptor activation.PAQR3 regulates Golgi vesicle fission and transport via the Gβγ-PKD signaling pathway.Regulation of PKD1-mediated Golgi to cell surface trafficking by Gαq subunits.Alteration of Golgi structure in senescent cells and its regulation by a G protein γ subunit.Minireview: Targeting GPCR Activated ERK Pathways for Drug Discovery.Real-time detection of G protein activation using monomolecular Gγ FRET sensors.Gγ identity dictates efficacy of Gβγ signaling and macrophage migration.Geranylgeranylation signals to the Hippo pathway for breast cancer cell proliferation and migration.Blue light excited retinal intercepts cellular signaling.
P2860
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P2860
A family of G protein βγ subunits translocate reversibly from the plasma membrane to endomembranes on receptor activation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
A family of G protein βγ subun ...... branes on receptor activation.
@ast
A family of G protein βγ subun ...... branes on receptor activation.
@en
type
label
A family of G protein βγ subun ...... branes on receptor activation.
@ast
A family of G protein βγ subun ...... branes on receptor activation.
@en
prefLabel
A family of G protein βγ subun ...... branes on receptor activation.
@ast
A family of G protein βγ subun ...... branes on receptor activation.
@en
P2093
P2860
P356
P1476
A family of G protein βγ subun ...... branes on receptor activation.
@en
P2093
Deepak Kumar Saini
Mariangela Chisari
Narasimhan Gautam
Vani Kalyanaraman
P2860
P304
24099-24108
P356
10.1074/JBC.M701191200
P407
P577
2007-06-20T00:00:00Z