Base damage immediately upstream from double-strand break ends is a more severe impediment to nonhomologous end joining than blocked 3'-termini
about
The dynamics of Ku70/80 and DNA-PKcs at DSBs induced by ionizing radiation is dependent on the complexity of damageProcessing of damaged DNA ends for double-strand break repair in mammalian cellsExposure to heavy ion radiation induces persistent oxidative stress in mouse intestineNonhomologous end joining: a good solution for bad endsRadiation-generated short DNA fragments may perturb non-homologous end-joining and induce genomic instabilityNon-homologous end joining: emerging themes and unanswered questions.Effects of indirect actions and oxygen on relative biological effectiveness: estimate of DSB induction and conversion induced by gamma rays and helium ions.Tyrosyl-DNA phosphodiesterase 1 (TDP1) repairs DNA damage induced by topoisomerases I and II and base alkylation in vertebrate cells.Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends.An in vitro DNA double-strand break repair assay based on end-joining of defined duplex oligonucleotidesNonhomologous end joining of complex DNA double-strand breaks with proximal thymine glycol and interplay with base excision repairTrimming of damaged 3' overhangs of DNA double-strand breaks by the Metnase and Artemis endonucleasesTherapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production.Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining.
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P2860
Base damage immediately upstream from double-strand break ends is a more severe impediment to nonhomologous end joining than blocked 3'-termini
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Base damage immediately upstre ...... oining than blocked 3'-termini
@ast
Base damage immediately upstre ...... oining than blocked 3'-termini
@en
type
label
Base damage immediately upstre ...... oining than blocked 3'-termini
@ast
Base damage immediately upstre ...... oining than blocked 3'-termini
@en
prefLabel
Base damage immediately upstre ...... oining than blocked 3'-termini
@ast
Base damage immediately upstre ...... oining than blocked 3'-termini
@en
P2093
P2860
P356
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Base damage immediately upstre ...... oining than blocked 3'-termini
@en
P2093
Elzbieta Pastwa
Kamal Datta
Ronald D Neumann
Shubhadeep Purkayastha
Thomas A Winters
P2860
P304
P356
10.1667/RR2332.1
P577
2011-01-01T00:00:00Z