Podocytes use FcRn to clear IgG from the glomerular basement membrane.
about
Mesangial cell-specific antibodies are central to the pathogenesis of lupus nephritisThe function of endocytosis in podocytesUnraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based TherapeuticsNovel siRNA delivery system to target podocytes in vivoTargeting FcRn for the modulation of antibody dynamicsKey factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and developmentNeonatal Fc receptor and IgG-based therapeuticsArhgap24 inactivates Rac1 in mouse podocytes, and a mutant form is associated with familial focal segmental glomerulosclerosisA high-powered view of the filtration barrier.Building an atlas of gene expression driving kidney development: pushing the limits of resolution.Development of Romiplostim for Treatment of Primary Immune Thrombocytopenia From a Pharmacokinetic and Pharmacodynamic Perspective.Human podocytes perform polarized, caveolae-dependent albumin endocytosis.A new function for parietal epithelial cells: a second glomerular barrier.Podocytes degrade endocytosed albumin primarily in lysosomesExprEssence--revealing the essence of differential experimental data in the context of an interaction/regulation net-workRediscovering Beta-2 Microglobulin As a Biomarker across the Spectrum of Kidney Diseases.Toward the development of podocyte-specific drugs.Involvement of Fc receptors in disorders of the central nervous system.Albumin-induced apoptosis of glomerular parietal epithelial cells is modulated by extracellular signal-regulated kinase 1/2The glomerulus--a view from the outside--the podocyte.Defining the molecular character of the developing and adult kidney podocyte.Neonatal Fc receptor: from immunity to therapeuticsInvolvement of the tubular ClC-type exchanger ClC-5 in glomeruli of human proteinuric nephropathies.Podocytes are nonhematopoietic professional antigen-presenting cells.Bovine FcRn-mediated human immunoglobulin G transfer across the milk-blood barrier in transgenic mice.Regulation of immune responses by the neonatal fc receptor and its therapeutic implicationsNeonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells.Glomerular endothelial cell injury and cross talk in diabetic kidney diseaseRole of the podocyte in proteinuria.Review series: The cell biology of renal filtration.FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin.Prorenin receptor is essential for normal podocyte structure and functionInvestigation of the mechanism of clearance of AMG 386, a selective angiopoietin-1/2 neutralizing peptibody, in splenectomized, nephrectomized, and FcRn knockout rodent models.Albumin-associated free fatty acids induce macropinocytosis in podocytes.Monoclonal antibodies directed against human FcRn and their applications.Anti-carcinoembryonic antigen single-chain variable fragment antibody variants bind mouse and human neonatal Fc receptor with different affinities that reveal distinct cross-species differences in serum half-lifeShank2 Regulates Renal Albumin Endocytosis.An Extended Minimal Physiologically Based Pharmacokinetic Model: Evaluation of Type II Diabetes Mellitus and Diabetic Nephropathy on Human IgG Pharmacokinetics in RatsHIV-associated nephropathy patients with and without apolipoprotein L1 gene variants have similar clinical and pathological characteristicsIntravenous immunoglobulin in the management of lupus nephritis.
P2860
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P2860
Podocytes use FcRn to clear IgG from the glomerular basement membrane.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Podocytes use FcRn to clear IgG from the glomerular basement membrane.
@ast
Podocytes use FcRn to clear IgG from the glomerular basement membrane.
@en
type
label
Podocytes use FcRn to clear IgG from the glomerular basement membrane.
@ast
Podocytes use FcRn to clear IgG from the glomerular basement membrane.
@en
prefLabel
Podocytes use FcRn to clear IgG from the glomerular basement membrane.
@ast
Podocytes use FcRn to clear IgG from the glomerular basement membrane.
@en
P2093
P2860
P50
P356
P1476
Podocytes use FcRn to clear IgG from the glomerular basement membrane.
@en
P2093
Andrey S Shaw
Björn Hartleben
Derry C Roopenian
Jeffrey H Miner
Tobias B Huber
P2860
P304
P356
10.1073/PNAS.0711515105
P407
P577
2008-01-15T00:00:00Z