Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy - Wikidata - awgldk - TriplyDB

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

http://www.wikidata.org/entity/Q36459468

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KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment Genetics and biology of pancreatic ductal adenocarcinoma Therapeutic Targeting of Autophagy Autophagy-Dependent Secretion: Contribution to Tumor Progression Autophagy inhibition overcomes multiple mechanisms of resistance to BRAF inhibition in brain tumors Cytotoxic Indole Alkaloid 3α-Acetonyltabersonine Induces Glioblastoma Apoptosis via Inhibition of DNA Damage Repair.Choose and Use Your Chemical Probe Wisely to Explore Cancer Biology.Nanomedicine strategies to overcome the pathophysiological barriers of pancreatic cancer.Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62 Mechanisms of Selective Autophagy in Normal Physiology and Cancer Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells.Recent insights into the function of autophagy in cancer.Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors.Lysosomotropism depends on glucose: a chloroquine resistance mechanism Chloroquine-Modified Hydroxyethyl Starch as a Polymeric Drug for Cancer Therapy.Targeting metabolic reprogramming in KRAS-driven cancers.NF-κB Signaling Activation Induced by Chloroquine Requires Autophagosome, p62 Protein, and c-Jun N-terminal Kinase (JNK) Signaling and Promotes Tumor Cell Resistance.Non-cell-autonomous Effects of Autophagy Inhibition in Tumor Cells Promote Growth of Drug-resistant Cells.Molecular definitions of autophagy and related processes.Autophagy is required for cell survival under L-asparaginase-induced metabolic stress in acute lymphoblastic leukemia cells.Autophagy is not uniformly cytoprotective: a personalized medicine approach for autophagy inhibition as a therapeutic strategy in non-small cell lung cancer.Molecular Pathways Controlling Autophagy in Pancreatic Cancer.Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment.The interplay between autophagy and tumorigenesis: exploiting autophagy as a means of anticancer therapy.Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.Autophagy in natural and therapy-driven anticancer immunosurveillance.Assays to Monitor Autophagy Progression in Cell Cultures.The Challenge of Developing Autophagy Inhibition as a Therapeutic Strategy.Autophagy and Inflammatory Response in the Tumor Microenvironment.ATG7 promotes the tumorigenesis of lung cancer but might be dispensable for prognosis predication: a clinicopathologic study ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells.Synthesis and Evaluation of Chloroquine-Containing DMAEMA Copolymers as Efficient Anti-miRNA Delivery Vectors with Improved Endosomal Escape and Antimigratory Activity in Cancer Cells.Targeting autophagy in cancer.Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine.Polymeric chloroquine as an inhibitor of cancer cell migration and experimental lung metastasis.Targeted Inhibition of EGFR and Glutaminase Induces Metabolic Crisis in EGFR Mutant Lung Cancer.N-(1-Benzyl-3,5-dimethyl-1H-pyrazol-4-yl)benzamides: Antiproliferative Activity and Effects on mTORC1 and Autophagy.Inhibition of autophagy initiation potentiates chemosensitivity in mesothelioma.Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.Targeting the Lysosome for Cancer Therapy.

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Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

http://www.wikidata.org/entity/Q36459468

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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name

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

@ast

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

@en

type

label

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

@ast

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

@en

prefLabel

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

@ast

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

@en

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy

@en

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Beat Nyfeler

http://www.w3.org/2001/XMLSchema#string

Christina H Eng

http://www.w3.org/2001/XMLSchema#string

Diane Tkach

http://www.w3.org/2001/XMLSchema#string

Elizabeth Frias

http://www.w3.org/2001/XMLSchema#string

Elizabeth George

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Gregory McAllister

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Gregory R Hoffman

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Judy Lucas

http://www.w3.org/2001/XMLSchema#string

Kevin Bray

http://www.w3.org/2001/XMLSchema#string

Leon O Murphy

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P2860

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Autophagy in malignant transformation and cancer progression

Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo

Autophagy fights disease through cellular self-digestion

A ubiquitin-like system mediates protein lipidation.

Induction of autophagy and inhibition of tumorigenesis by beclin 1

Selective autophagy mediated by autophagic adapter proteins

EGFR tyrosine kinase inhibitors activate autophagy as a cytoprotective response in human lung cancer cells

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

The role of autophagy during the early neonatal starvation period

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113

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26677873

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