Design of composite inhibitors targeting glutamate carboxypeptidase II: the importance of effector functionalities

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Design of composite inhibitors targeting glutamate carboxypeptidase II: the importance of effector functionalities

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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Design of composite inhibitors ...... ce of effector functionalities

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Design of composite inhibitors ...... ce of effector functionalities

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Design of composite inhibitors ...... ce of effector functionalities

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Design of composite inhibitors ...... ce of effector functionalities

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Design of composite inhibitors ...... ce of effector functionalities

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Design of composite inhibitors ...... ce of effector functionalities

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P1476

Design of composite inhibitors ...... ce of effector functionalities

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P2093

Cindy J Choy

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Clifford E Berkman

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Jacek Lubkowski

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Joeseph K Choi

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Zora Novakova

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P2860

Structural and biochemical characterization of the folyl-poly-γ-l-glutamate hydrolyzing activity of human glutamate carboxypeptidase II

Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer

MolProbity: all-atom structure validation for macromolecular crystallography

A high-resolution structure of ligand-free human glutamate carboxypeptidase II

Human glutamate carboxypeptidase II inhibition: structures of GCPII in complex with two potent inhibitors, quisqualate and 2-PMPA

Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II

Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs

Interactions between human glutamate carboxypeptidase II and urea-based inhibitors: structural characterization

Bioisosterism of urea-based GCPII inhibitors: Synthesis and structure–activity relationship studies

A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules.

P304

130-143

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scholarly article

P356

10.1111/FEBS.13557

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P407

English

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P478

283

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P50

Cyril Barinka

Jiri Cerny

Jessie R Nedrow

P577

2015-11-05T00:00:00Z

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P698

26460595

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P932

4712110

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