Dual roles of PARP-1 promote cancer growth and progression. - Wikidata - awgldk - TriplyDB

Dual roles of PARP-1 promote cancer growth and progression.

Dual roles of PARP-1 promote cancer growth and progression.

http://www.wikidata.org/entity/Q36460391

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Safe handling of oral antineoplastic medications: focus on targeted therapeutics in the home setting Therapeutic Implications for Overcoming Radiation Resistance in Cancer Therapy Chromatin Dynamics in Vivo: A Game of Musical Chairs Beyond DNA repair: DNA-PK function in cancer DNA damage response and prostate cancer: defects, regulation and therapeutic implications Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer The convergence of DNA damage checkpoint pathways and androgen receptor signaling in prostate cancer Targeting the adaptive molecular landscape of castration-resistant prostate cancer DNA damage response genes and the development of cancer metastasis Targeting DNA repair with combination veliparib (ABT-888) and temozolomide in patients with metastatic castration-resistant prostate cancer Androgen synthesis inhibitors in the treatment of castration-resistant prostate cancer.Poly (ADP-ribose) polymerase inhibitor: an evolving paradigm in the treatment of prostate cancer.Genomic profile of human meningioma cell lines.Combination Platinum-based and DNA Damage Response-targeting Cancer Therapy: Evolution and Future Directions.Targeting poly(ADP-ribose) polymerase and the c-Myb-regulated DNA damage response pathway in castration-resistant prostate cancer.Basal activity of a PARP1-NuA4 complex varies dramatically across cancer cell lines.Molecular pathways and targets in prostate cancer PARP-1 regulates epithelial-mesenchymal transition (EMT) in prostate tumorigenesis EPI-001 is a selective peroxisome proliferator-activated receptor-gamma modulator with inhibitory effects on androgen receptor expression and activity in prostate cancer Consequence of the tumor-associated conversion to cyclin D1b The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1.PARP1 Inhibitors: antitumor drug design.Active FOXO1 Is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming.Linking DNA Damage and Hormone Signaling Pathways in Cancer.Mitotic bookmarking: maintaining post-mitotic reprogramming of transcription reactivation Of Mice and Melanoma: PDX System for Modeling Personalized Medicine.Differential Effects of Estradiol and Bisphenol A on SET8 and SIRT1 Expression in Ovarian Cancer Cells.A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthones.Post-transcriptional regulation by poly(ADP-ribosyl)ation of the RNA-binding proteins.Differential regulation of cell death programs in males and females by Poly (ADP-Ribose) Polymerase-1 and 17β estradiol PKCα and HMGB1 antagonistically control hydrogen peroxide-induced poly-ADP-ribose formation.Targeted radiosensitization of ETS fusion-positive prostate cancer through PARP1 inhibition.A hormone-DNA repair circuit governs the response to genotoxic insult Beyond DNA Repair: Additional Functions of PARP-1 in Cancer.Small interfering RNA-mediated silencing of nicotinamide phosphoribosyltransferase (NAMPT) and lysosomal trafficking regulator (LYST) induce growth inhibition and apoptosis in human multiple myeloma cells: A preliminary study.The Correlation Between PARP1 and BRCA1 in AR Positive Triple-negative Breast Cancer.Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer.Molecular pathways: targeting resistance in the androgen receptor for therapeutic benefit Targeting DNA Repair in Cancer: Beyond PARP Inhibitors.PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.

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P2860

Dual roles of PARP-1 promote cancer growth and progression.

http://www.wikidata.org/entity/Q36460391

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2012年学术文章

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2012年學術文章

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2012年學術文章

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2012年學術文章

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Dual roles of PARP-1 promote cancer growth and progression.

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Dual roles of PARP-1 promote cancer growth and progression.

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Dual roles of PARP-1 promote cancer growth and progression.

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Dual roles of PARP-1 promote cancer growth and progression.

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Dual roles of PARP-1 promote cancer growth and progression.

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Dual roles of PARP-1 promote cancer growth and progression.

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Cancer Discovery

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Dual roles of PARP-1 promote cancer growth and progression.

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Felix Y Feng

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Fengzhi Liu

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Ganesh V Raj

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J Chad Brenner

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Jonathan F Goodwin

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Jonathan R Brody

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P2860

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer

Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

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Karen E Knudsen

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