Preclinical activity of the novel B-cell-specific Moloney murine leukemia virus integration site 1 inhibitor PTC-209 in acute myeloid leukemia: Implications for leukemia therapy
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Targeting of BMI-1 with PTC-209 shows potent anti-myeloma activity and impairs the tumour microenvironment.Concise Review: Emerging Drugs Targeting Epithelial Cancer Stem-Like Cells.The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells.Knockdown of Sall4 inhibits intrahepatic cholangiocarcinoma cell migration and invasion in ICC-9810 cells.Synthesis and Characterization of Novel BMI1 Inhibitors Targeting Cellular Self-Renewal in Hepatocellular Carcinoma.Pharmacological inhibition of Bmi1 by PTC-209 impaired tumor growth in head neck squamous cell carcinoma.Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes.Targeting of BMI-1 expression by the novel small molecule PTC596 in mantle cell lymphoma.
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P2860
Preclinical activity of the novel B-cell-specific Moloney murine leukemia virus integration site 1 inhibitor PTC-209 in acute myeloid leukemia: Implications for leukemia therapy
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2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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name
Preclinical activity of the no ...... lications for leukemia therapy
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Preclinical activity of the no ...... lications for leukemia therapy
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type
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Preclinical activity of the no ...... lications for leukemia therapy
@ast
Preclinical activity of the no ...... lications for leukemia therapy
@en
prefLabel
Preclinical activity of the no ...... lications for leukemia therapy
@ast
Preclinical activity of the no ...... lications for leukemia therapy
@en
P2093
P2860
P356
P1433
P1476
Preclinical activity of the no ...... lications for leukemia therapy
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P2093
Jo Ishizawa
Kensuke Kojima
Shinya Kimura
Steven M Kornblau
Yi Hua Qiu
Yuki Nishida
P2860
P304
P356
10.1111/CAS.12833
P577
2015-10-09T00:00:00Z