Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
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Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channelUbiquitylation and control of renal Na+ balance and blood pressureRegulation and dysregulation of epithelial Na+ channelsVasopressin-inducible ubiquitin-specific protease 10 increases ENaC cell surface expression by deubiquitylating and stabilizing sorting nexin 3AS160 modulates aldosterone-stimulated epithelial sodium channel forward traffickingEndothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2.The N-terminal 81-aa fragment is critical for UT-A1 urea transporter bioactivity.Regulation of sodium transport by ENaC in the kidneyCys palmitoylation of the beta subunit modulates gating of the epithelial sodium channelUbiquitin-specific protease 2-45 (Usp2-45) binds to epithelial Na+ channel (ENaC)-ubiquitylating enzyme Nedd4-2.Ubiquitination of aquaporin-2 in the kidney.Genetic screening of SCNN1B and SCNN1G genes in early-onset hypertensive patients helps to identify Liddle syndrome.Saccharomyces cerivisiae as a model system for kidney disease: what can yeast tell us about renal function?Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung.Regulation of alveolar epithelial Na+ channels by ERK1/2 in chlorine-breathing mice.Exosomal GAPDH from Proximal Tubule Cells Regulate ENaC Activity.Regulation of transport in the connecting tubule and cortical collecting ductCOMMD proteins: COMMing to the scene.Deubiquitylation regulates activation and proteolytic cleavage of ENaCMDM2 E3 ubiquitin ligase mediates UT-A1 urea transporter ubiquitination and degradation.Regulation of the epithelial sodium channel by membrane trafficking.Hsc70 negatively regulates epithelial sodium channel trafficking at multiple sites in epithelial cells.Ubiquitylation of Fe65 adaptor protein by neuronal precursor cell expressed developmentally down regulated 4-2 (Nedd4-2) via the WW domain interaction with Fe65.Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species.Effect of apical hyperosmotic sodium challenge and amiloride on sodium transport in human bronchial epithelial cells from cystic fibrosis donors.Activation of the cAMP/PKA pathway induces UT-A1 urea transporter monoubiquitination and targets it for lysosomal degradationAntiepileptic drugs reduce the efficacy of methotrexate chemotherapy through accelerated degradation of the reduced folate carrier by the ubiquitin-proteasome pathway.The role of ubiquitination in hepcidin-independent and hepcidin-dependent degradation of ferroportin.Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B.NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.Restoration of Epithelial Sodium Channel Function by Synthetic Peptides in Pseudohypoaldosteronism Type 1B Mutants.Maresin1 stimulates alveolar fluid clearance through the alveolar epithelial sodium channel Na,K-ATPase via the ALX/PI3K/Nedd4-2 pathway.Regulation of the delta and alpha epithelial sodium channel (ENaC) by ubiquitination and Nedd8.ENaC channels in oocytes from Xenopus laevis and their regulation by xShroom1 protein.
P2860
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P2860
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
@ast
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
@en
type
label
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
@ast
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
@en
prefLabel
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
@ast
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
@en
P2093
P1476
Regulation of epithelial sodium channels by the ubiquitin-proteasome proteolytic pathway.
@en
P2093
P304
P356
10.1152/AJPRENAL.00432.2005
P577
2006-06-01T00:00:00Z