Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
about
Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selectionAberrant Wnt Signaling in LeukemiaRoles of transcriptional factor 7 in production of inflammatory factors for lung diseasesWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentMicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and developmentGene-based outcome prediction in multiple cohorts of pediatric T-cell acute lymphoblastic leukemia: a Children's Oncology Group study.Peripheral T-lymphocytes express WNT7A and its restoration in leukemia-derived lymphoblasts inhibits cell proliferation.Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis.Cooperation between Wnt and Notch signalling in human breast cancer.Analysis of Rho GTPase expression in T-ALL identifies RhoU as a target for Notch involved in T-ALL cell migrationEffects of Toll-like receptor signals in T-cell neoplasms.Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo.Molecular basis for the tissue specificity of β-catenin oncogenesis.CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1-induced T-cell acute lymphoblastic leukemia.The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis.Therapeutic implications of leukemic stem cell pathwaysProapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia.Dual inhibition of class IA phosphatidylinositol 3-kinase and mammalian target of rapamycin as a new therapeutic option for T-cell acute lymphoblastic leukemia.Upsides and downsides to polarity and asymmetric cell division in leukemia.Role of Wnt canonical pathway in hematological malignancies.Epithelial-mesenchymal transition, the tumor microenvironment, and metastatic behavior of epithelial malignancies.Discovery and characterization of miRNAs in mouse thymus responses to ionizing radiation by deep sequencing.TNF-alpha and Notch signaling regulates the expression of HOXB4 and GATA3 during early T lymphopoiesis.Methylation of Wnt antagonist genes: a useful prognostic marker for myelodysplastic syndrome.CBP/Catenin antagonists: Targeting LSCs' Achilles heel.Arsenic trioxide increases expression of secreted frizzled-related protein 1 gene and inhibits the WNT/β-catenin signaling pathway in Jurkat cells.Genome-wide expression analysis of paired diagnosis-relapse samples in ALL indicates involvement of pathways related to DNA replication, cell cycle and DNA repair, independent of immune phenotype.
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P2860
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
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2006年學術文章
@zh-hant
name
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
@ast
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
@en
type
label
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
@ast
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
@en
prefLabel
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
@ast
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
@en
P2093
P2860
P356
P1433
P1476
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.
@en
P2093
Weerkamp F
van Dongen JJ
P2860
P2888
P304
P356
10.1038/SJ.LEU.2404255
P577
2006-05-11T00:00:00Z
P5875
P6179
1026617225