Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
about
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylaseSir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signalingSIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus.T cell metabolism drives immunityStructural basis for sirtuin activity and inhibitionProtective effects and mechanisms of sirtuins in the nervous systemRole of nutrient-sensing signals in the pathogenesis of diabetic nephropathySirtuin 1 and sirtuin 3: physiological modulators of metabolismLocal and regional chromatin silencing in Candida glabrata: consequences for adhesion and the response to stressThe role of mammalian sirtuins in the regulation of metabolism, aging, and longevityAging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicansSirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and AgingLysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationLinking metabolism and epigenetic regulation in development of hepatocellular carcinomaSirtuins in epigenetic regulationPlasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl LysineThe histone H3 lysine 56 acetylation pathway is regulated by target of rapamycin (TOR) signaling and functions directly in ribosomal RNA biogenesisSIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growthAdaptive cellular stress pathways as therapeutic targets of dietary phytochemicals: focus on the nervous systemβ-Lapachone ameliorates lipotoxic cardiomyopathy in acyl CoA synthase transgenic miceA nutrient-sensitive interaction between Sirt1 and HNF-1α regulates Crp expressionSir2a regulates rDNA transcription and multiplication rate in the human malaria parasite Plasmodium falciparumSirtuin activity in dentate gyrus contributes to chronic stress-induced behavior and extracellular signal-regulated protein kinases 1 and 2 cascade changes in the hippocampus.Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation.Enterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model.Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation.Transcriptional control of antioxidant defense by the circadian clockSIRT3 substrate specificity determined by peptide arrays and machine learning.Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulationPotent and orally efficacious bisthiazole-based histone deacetylase inhibitorsDrosophila Sirt2/mammalian SIRT3 deacetylates ATP synthase β and regulates complex V activity.PARP inhibition delays progression of mitochondrial encephalopathy in mice.Compartmentation of NAD+-dependent signalling.CREB and the CRTC co-activators: sensors for hormonal and metabolic signalsNAD+-dependent sirtuin 1 and 6 proteins coordinate a switch from glucose to fatty acid oxidation during the acute inflammatory response.dSir2 and longevity in Drosophila.Sirtuin catalysis and regulationLeucine Modulates Mitochondrial Biogenesis and SIRT1-AMPK Signaling in C2C12 Myotubes.Regulation of NAD+ metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiaeRegulation of the mPTP by SIRT3-mediated deacetylation of CypD at lysine 166 suppresses age-related cardiac hypertrophy.
P2860
Q24296766-DFA6E906-F74B-4877-AEDC-109CB43C5D27Q24338727-B15C319D-F983-40C4-B294-B813059C713CQ24630974-4C52C9E0-809A-4AFA-B077-BFD74A448AE5Q26799575-1DCD8065-2016-4E22-B6A4-A7213354D023Q26823308-B0675214-27C7-44F9-94C9-FA8B28EA9775Q26825585-4577958D-517B-47F1-B9A9-AA77DBBBEFD2Q26828026-E0E9F55F-3D49-457E-B8AA-FE406A6EB63FQ26828607-42162AA9-0059-48A9-B5F4-FF39AEFEB912Q26864043-486644DF-62D3-42F3-8034-DFC1606EFA38Q26865526-324B88A4-8451-4DA3-A78A-8C229B55D5E9Q26866874-FC6BBF73-3BB4-41F0-8B36-4C41B7E3BC09Q27021755-709BF2DD-5015-4E2D-BCAF-7473F98E1B83Q27021965-C28AEB9B-3EAD-4930-99A2-7E6FD6ACF696Q27023744-0DC531A4-8453-4043-8A6E-C78A23449B0FQ27026861-C45A9389-8AD4-4766-BAB8-11F06269FD0BQ27674991-E418D0A3-F476-402D-8DA6-AFE09F1A2E1CQ27936099-20F7A666-B769-4739-8B3C-A654897E50D3Q28258574-22EF0D5E-0F07-4679-88E6-5F02F47C00AEQ28389419-43A6139F-46A9-49ED-8C18-808605385F6FQ28540678-1CAB734F-9F55-4D36-8F23-F3560258B09EQ28586675-97E3ED8F-577B-4D18-A974-F29A147FD7A7Q30046047-53439BB1-2766-480F-9B13-8DDE5D5A0E89Q30411171-AFC750EB-0EC4-4D7A-B190-0C28652829F6Q30570559-29761F22-1F03-49ED-9DE7-F5530B51E0F3Q31120854-C91BE2EB-F416-467C-BC2E-8D1657B06D42Q33676590-D747AE16-0F7A-4C7A-AA70-3186E82E3500Q33687785-2282DFF3-EFA9-4B2F-82D8-A3E3EF6CBA7CQ33718384-861863C9-979C-4DCE-ABC5-14F56C362224Q33731432-5C8D11DC-0956-46A8-A0FB-A56F2E37B6ECQ33768549-626692A2-A38F-4815-B00A-75796AEC2DF0Q33937684-749652E5-95E8-4112-9294-FDB022E35ED0Q34000773-8345DE57-3926-4C5D-AA33-13F24DF85BE3Q34026322-67DCF54B-FB56-4D78-8C16-5409CE6909A9Q34166530-3CE37022-4ACB-4F57-83EF-CFF55CE34843Q34281758-C0B39ECB-2444-4BC1-A6AE-CBFD7BE58B43Q34380542-1FD2F7BA-B259-4594-8D6E-A58E2FDDC9BCQ34453795-0A0A9B29-BA7C-431C-B5D7-6E69F0EEE974Q34454206-42B298F2-0C97-4625-8E0F-C01689E11256Q34622726-0CC0283D-58DC-44D3-9695-D9EB6F2ACA17Q34626193-957806D1-ED0A-4023-AA6B-2F0FC79725E6
P2860
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
@ast
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
@en
type
label
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
@ast
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
@en
prefLabel
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
@ast
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
@en
P2860
P1476
Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.
@en
P2093
Leonard Guarente
Shin-ichiro Imai
P2860
P304
P356
10.1016/J.TIPS.2010.02.003
P577
2010-03-11T00:00:00Z