Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl
about
AXL kinase as a novel target for cancer therapyThe microRNA feedback regulation of p63 in cancer progressionRole of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations.Design, synthesis, and validation of Axl-targeted monoclonal antibody probe for microPET imaging in human lung cancer xenograft.Mutation or loss of p53 differentially modifies TGFβ action in ovarian cancerAxl receptor tyrosine kinase is up-regulated in metformin resistant prostate cancer cells.A novel TP53 pathway influences the HGS-mediated exosome formation in colorectal cancer.TP53 mutants in the tower of babel of cancer progression.Preferred binding of gain-of-function mutant p53 to bidirectional promoters with coordinated binding of ETS1 and GABPA to multiple binding sites.Role of AXL expression in non-small cell lung cancer.Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination.Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells.Oncogenic Mutant p53 Gain of Function Nourishes the Vicious Cycle of Tumor Development and Cancer Stem-Cell Formation.Increased tumor cell expression of Axl is a marker of aggressive features in breast cancer among African women.Transcriptional Regulation by Wild-Type and Cancer-Related Mutant Forms of p53.AXL receptor tyrosine kinase as a therapeutic target in NSCLC.Key Roles of AXL and MER Receptor Tyrosine Kinases in Resistance to Multiple Anticancer Therapies.Nedaplatin sensitization of cisplatin-resistant human non-small cell lung cancer cells.Axl Receptor Axis: A New Therapeutic Target in Lung Cancer.AXL-GAS6 expression can predict for adverse prognosis in non-small cell lung cancer with brain metastases.Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter.Clinical significance of different types of p53 gene alteration in surgically treated prostate cancer.
P2860
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P2860
Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Gain-of-Function Activity of M ...... or Protein Tyrosine Kinase Axl
@ast
Gain-of-Function Activity of M ...... or Protein Tyrosine Kinase Axl
@en
type
label
Gain-of-Function Activity of M ...... or Protein Tyrosine Kinase Axl
@ast
Gain-of-Function Activity of M ...... or Protein Tyrosine Kinase Axl
@en
prefLabel
Gain-of-Function Activity of M ...... or Protein Tyrosine Kinase Axl
@ast
Gain-of-Function Activity of M ...... or Protein Tyrosine Kinase Axl
@en
P2093
P2860
P356
P1433
P1476
Gain-of-Function Activity of M ...... or Protein Tyrosine Kinase Axl
@en
P2093
Brad Windle
Catherine A Vaughan
Rebecca Frum
Shilpa Singh
Steven R Grossman
Sumitra Deb
Swati P Deb
W Andrew Yeudall
P2860
P304
P356
10.1177/1947601912462719
P577
2012-07-01T00:00:00Z