The ATP-binding cassette transporters and their implication in drug disposition: a special look at the heart.
about
Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytesBioengineered 3D human kidney tissue, a platform for the determination of nephrotoxicitySystemic gut microbial modulation of bile acid metabolism in host tissue compartments.Imatinib and nilotinib reverse multidrug resistance in cancer cells by inhibiting the efflux activity of the MRP7 (ABCC10).Adriamycin nephropathy: a failure of endothelial progenitor cell-induced repair.Endothelial progenitors encapsulated in bioartificial niches are insulated from systemic cytotoxicity and are angiogenesis competentAfatinib circumvents multidrug resistance via dually inhibiting ATP binding cassette subfamily G member 2 in vitro and in vivo.Drug transporters, the blood-testis barrier, and spermatogenesisAscites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells.Murine hyperglycemic vasculopathy and cardiomyopathy: whole-genome gene expression analysis predicts cellular targets and regulatory networks influenced by mannose binding lectinToxic Diatom Aldehydes Affect Defence Gene Networks in Sea UrchinsLoss of multidrug resistance-associated protein 1 potentiates chronic doxorubicin-induced cardiac dysfunction in mice.A combination of sorafenib and nilotinib reduces the growth of castrate-resistant prostate cancer.Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein.MRP (ABCC) transporters-mediated efflux of anti-HIV drugs, saquinavir and zidovudine, from human endothelial cells.Psorospermin structural requirements for P-glycoprotein resistance reversal.Transporter-mediated uptake into cellular compartments.An intracellular trafficking pathway in the seminiferous epithelium regulating spermatogenesis: a biochemical and molecular perspective.Regulation of human hepatic drug transporter expression by pro-inflammatory cytokines.Unexpected doxorubicin-mediated cardiotoxicity in sisters: possible role of polymorphisms in histamine n-methyl transferase.Influence of efflux transporters on drug metabolism: theoretical approach for bioavailability and clearance prediction.Functional characterization of drug uptake and metabolism in the heart.Systems biology approaches to adverse drug effects: the example of cardio-oncology.Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.Structure-activity relationships, ligand efficiency, and lipophilic efficiency profiles of benzophenone-type inhibitors of the multidrug transporter P-glycoprotein.Scutellarin protects against doxorubicin-induced acute cardiotoxicity and regulates its accumulation in the heartAssessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination.Gender-related differences in drug-induced prolongation of cardiac repolarization in prepubertal guinea pigs.Modulatory role of verapamil treatment on the cardiac electrophysiological effects of cisapride.Creatine supplementation reduces doxorubicin-induced cardiomyocellular injury.Role of P-glycoprotein in restricting the brain penetration of tanshinone IIA, a major active constituent from the root of Salvia miltiorrhiza Bunge, across the blood-brain barrier.FGF-2 protects cardiomyocytes from doxorubicin damage via protein kinase C-dependent effects on efflux transporters.Targeting the Multidrug Transporter Ptch1 Potentiates Chemotherapy Efficiency
P2860
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P2860
The ATP-binding cassette transporters and their implication in drug disposition: a special look at the heart.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
The ATP-binding cassette trans ...... : a special look at the heart.
@ast
The ATP-binding cassette trans ...... : a special look at the heart.
@en
type
label
The ATP-binding cassette trans ...... : a special look at the heart.
@ast
The ATP-binding cassette trans ...... : a special look at the heart.
@en
prefLabel
The ATP-binding cassette trans ...... : a special look at the heart.
@ast
The ATP-binding cassette trans ...... : a special look at the heart.
@en
P2093
P356
P1476
The ATP-binding cassette trans ...... : a special look at the heart.
@en
P2093
Jacques Turgeon
John A Nash
Lucie Couture
P304
P356
10.1124/PR.58.2.7
P577
2006-06-01T00:00:00Z