CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis - Wikidata - awgldk - TriplyDB

CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis

CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis

http://www.wikidata.org/entity/Q36484503

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Hyaluronan (HA) interacting proteins RHAMM and hyaluronidase impact prostate cancer cell behavior and invadopodia formation in 3D HA-based hydrogels PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells Role of moesin in hyaluronan induced cell migration in glioblastoma multiforme Pharmacologic disruption of Polycomb Repressive Complex 2 inhibits tumorigenicity and tumor progression in prostate cancer Activation of signal transducer and activator of transcription 3 through a phosphomimetic serine 727 promotes prostate tumorigenesis independent of tyrosine 705 phosphorylation The androgen receptor and stem cell pathways in prostate and bladder cancers (review)Targeting prostate cancer stem cells for cancer therapy Prostate cancer and parasitism of the bone hematopoietic stem cell niche Prostate Cancer Stem Cells: Research Advances The role of prostate tumor overexpressed 1 in cancer progression Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?The cancer stem cell niche--there goes the neighborhood?Udp-glucose dehydrogenase as a novel field-specific candidate biomarker of prostate cancer A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept CD24 Expression May Play a Role as a Predictive Indicator and a Modulator of Cisplatin Treatment Response in Head and Neck Squamous Cellular Carcinoma Microenvironmental modulation of asymmetric cell division in human lung cancer cells.The CD44(high) tumorigenic subsets in lung cancer biospecimens are enriched for low miR-34a expression.Identification, characterization, and biological relevance of prostate cancer stem cells from clinical specimens.Genomic profiling of tumor initiating prostatospheres.A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children.Sulforaphane and TRAIL induce a synergistic elimination of advanced prostate cancer stem-like cells Gossypol induces apoptosis by activating p53 in prostate cancer cells and prostate tumor-initiating cells.More than markers: biological significance of cancer stem cell-defining molecules.Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters.Revisiting epithelial-mesenchymal transition in cancer metastasis: the connection between epithelial plasticity and stemness.The human airway epithelial basal cell transcriptome.Chemopreventive effect of PSP through targeting of prostate cancer stem cell-like population.Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target.GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state Screening of peptides bound to breast cancer stem cell specific surface marker CD44 by phage display.Activation of c-MET induces a stem-like phenotype in human prostate cancer Prostate cancer cell lines under hypoxia exhibit greater stem-like properties.Primitive origins of prostate cancer: in vivo evidence for prostate-regenerating cells and prostate cancer-initiating cells Cell-to-cell signaling influences the fate of prostate cancer stem cells and their potential to generate more aggressive tumors.Conversion of stationary to invasive tumor initiating cells (TICs): role of hypoxia in membrane type 1-matrix metalloproteinase (MT1-MMP) trafficking A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells.Sulforaphane increases drug-mediated cytotoxicity toward cancer stem-like cells of pancreas and prostate.Targeting proapoptotic protein BAD inhibits survival and self-renewal of cancer stem cells

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CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis

http://www.wikidata.org/entity/Q36484503

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British Journal of Cancer

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CD44+ CD24(-) prostate cells a ...... r patients with poor prognosis

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B T Kawasaki

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E M Hurt

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G J Klarmann

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S B Thomas

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W L Farrar

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P2860

Prospective identification of tumorigenic breast cancer cells

Identification and expansion of human colon-cancer-initiating cells

A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

Stem cells, cancer, and cancer stem cells

Identification of human brain tumour initiating cells

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

A tumorigenic subpopulation with stem cell properties in melanomas

Identification of pancreatic cancer stem cells

Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

Prospective identification of tumorigenic prostate cancer stem cells

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