Cloning of the E. coli O6-methylguanine and methylphosphotriester methyltransferase gene using a functional DNA repair assay.
about
Regulatory responses of the adaptive response to alkylation damage: a simple regulon with complex regulatory featuresRepair of O-alkylpyrimidines in mammalian cells: a present consensus.Stereospecific removal of methyl phosphotriesters from DNA by an Escherichia coli ada+ extract.Alteration of lysine 178 in the hinge region of the Escherichia coli ada protein interferes with activation of ada, but not alkA, transcription.The Ada protein acts as both a positive and a negative modulator of Escherichia coli's response to methylating agents.Purification to apparent homogeneity and partial amino acid sequence of rat liver O6-alkylguanine-DNA-alkyltransferaseBacillus subtilis ada operon encodes two DNA alkyltransferases.Expression of a human O6-alkylguanine-DNA-alkyltransferase cDNA in human cells and transgenic mice.Phosphotriester formation by the haloethylnitrosoureas and repair of these lesions by E. coli BS21 extracts.Rapid, large-scale purification and characterization of 'Ada protein' (O6 methylguanine-DNA methyltransferase) of E. coli.The Ada protein is a class I transcription factor of Escherichia coliSite-directed mutation of the Escherichia coli ada gene: effects of substitution of methyl acceptor cysteine-321 by histidine in Ada proteinCharacterization of the major DNA repair methyltransferase activity in unadapted Escherichia coli and identification of a similar activity in Salmonella typhimurium.Alteration of the carboxyl-terminal domain of Ada protein influences its inducibility, specificity, and strength as a transcriptional activatorMultiple species of Bacillus subtilis DNA alkyltransferase involved in the adaptive response to simple alkylating agentsMolecular analysis of Bacillus subtilis ada mutants deficient in the adaptive response to simple alkylating agentsCharacterisation and nucleotide sequence of ogt, the O6-alkylguanine-DNA-alkyltransferase gene of E. coli.Linkage map of Escherichia coli K-12, edition 8Relationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes.Suppression of human DNA alkylation-repair defects by Escherichia coli DNA-repair genes.Reduction of the toxicity and mutagenicity of alkylating agents in mammalian cells harboring the Escherichia coli alkyltransferase gene.Methyl transferases induced during chemical adaptation of M. luteus.Alkyl phosphotriester modified oligodeoxyribonucleotides. VI. NMR and UV spectroscopic studies of ethyl phosphotriester (Et) modified Rp-Rp and Sp-Sp duplexes, (d[GGAA(Et)TTCC])2.Inducible alkyltransferase DNA repair proteins in the filamentous fungus Aspergillus nidulans.Evidence that covalent complex formation between BCNU-treated oligonucleotides and E. coli alkyltransferases requires the O6-alkylguanine function.Expression of the ogt gene in wild-type and ada mutants of E. coli.Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.Mapping of OGT in the E.coli chromosome.Modification of genotoxicity by naturally occurring flavorings and their derivatives.Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents.Induced synthesis of O6-methylguanine-DNA methyltransferase in rat hepatoma cells exposed to DNA-damaging agents.Differential inactivation of mammalian and Escherichia coli O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine.Expression in mammalian cells of the Escherichia coli O6 alkylguanine-DNA-alkyltransferase gene ogt reduces the toxicity of alkylnitrosoureas.C-terminally truncated human O6-alkylguanine-DNA alkyltransferase retains activity.O6-alkylguanine-DNA-alkyltransferase activity and nitrosourea sensitivity in human cancer cell linesCompetition between NarL-dependent activation and Fis-dependent repression controls expression from the Escherichia coli yeaR and ogt promoters.
P2860
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P2860
Cloning of the E. coli O6-methylguanine and methylphosphotriester methyltransferase gene using a functional DNA repair assay.
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
Cloning of the E. coli O6-meth ...... a functional DNA repair assay.
@ast
Cloning of the E. coli O6-meth ...... a functional DNA repair assay.
@en
type
label
Cloning of the E. coli O6-meth ...... a functional DNA repair assay.
@ast
Cloning of the E. coli O6-meth ...... a functional DNA repair assay.
@en
prefLabel
Cloning of the E. coli O6-meth ...... a functional DNA repair assay.
@ast
Cloning of the E. coli O6-meth ...... a functional DNA repair assay.
@en
P2093
P2860
P356
P1476
Cloning of the E. coli O6-meth ...... a functional DNA repair assay.
@en
P2093
Brennand J
Margison GP
P2860
P304
P356
10.1093/NAR/13.6.1939
P407
P577
1985-03-01T00:00:00Z