Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
about
Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coliPharmacogenetics: detecting sensitive populationsIsolation and partial characterisation of a Chinese hamster O6-alkylguanine-DNA alkyltransferase cDNA.Purification to homogeneity and partial amino acid sequence of a fragment which includes the methyl acceptor site of the human DNA repair protein for O6-methylguanineDepletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.DNA damage related crosstalk between the nucleus and mitochondria.Fragmentation of electrospray-produced deprotonated ions of oligodeoxyribonucleotides containing an alkylated or oxidized thymidineCytotoxic and mutagenic properties of regioisomeric O²-, N3- and O⁴-ethylthymidines in bacterial cells.Quantitative relationship between guanine O(6)-alkyl lesions produced by Onrigin™ and tumor resistance by O(6)-alkylguanine-DNA alkyltransferase.Syntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the minor-groove O2-alkylthymidine lesions.Gene therapy to protect haematopoietic cells from cytotoxic cancer drugs.Genetic effects from exposure to hazardous agentsIn vitro DNA replication implicates O2-ethyldeoxythymidine in transversion mutagenesis by ethylating agents.The role of mutagenic metal ions in mediating in vitro mispairing by alkylpyrimidines.Purification to apparent homogeneity and partial amino acid sequence of rat liver O6-alkylguanine-DNA-alkyltransferaseCharacterization of the major DNA repair methyltransferase activity in unadapted Escherichia coli and identification of a similar activity in Salmonella typhimurium.Cytotoxic and mutagenic properties of O4-alkylthymidine lesions in Escherichia coli cells.In-vitro replication studies on O(2)-methylthymidine and O(4)-methylthymidineO6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.Quantitation of pyridyloxobutyl DNA adducts of tobacco-specific nitrosamines in rat tissue DNA by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometryMolecular cloning and expression pattern of rpr-1, a resiniferatoxin-binding, phosphotriesterase-related protein, expressed in rat kidney tubules.Replication across regioisomeric ethylated thymidine lesions by purified DNA polymerases.Replicative Bypass of O(2)-Alkylthymidine Lesions in Vitro.N-methylpurine DNA glycosylase plays a pivotal role in the threshold response of ethyl methanesulfonate-induced chromosome damage.In Vitro Lesion Bypass Studies of O(4)-Alkylthymidines with Human DNA Polymerase η.Evidence that covalent complex formation between BCNU-treated oligonucleotides and E. coli alkyltransferases requires the O6-alkylguanine function.Use of shuttle vectors to study the molecular processing of defined carcinogen-induced DNA damage: mutagenicity of single O4-ethylthymine adducts in HeLa cells.Expression of the ogt gene in wild-type and ada mutants of E. coli.Purification of the E. coli ogt gene product to homogeneity and its rate of action on O6-methylguanine, O6-ethylguanine and O4-methylthymine in dodecadeoxyribonucleotides.O-ethylthymidine adducts are the most relevant damages for mutation induced by N-ethyl-N-nitrosourea in female germ cells of Drosophila melanogaster.
P2860
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P2860
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
description
1988 nî lūn-bûn
@nan
1988 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի մարտին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@ast
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@en
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@nl
type
label
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@ast
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@en
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@nl
prefLabel
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@ast
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@en
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@nl
P2093
P2860
P356
P1476
Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
@en
P2093
G P Margison
H Fraenkel-Conrat
P M Potter
R Montesano
P2860
P304
P356
10.1073/PNAS.85.6.1759
P407
P577
1988-03-01T00:00:00Z