A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism - Wikidata - awgldk - TriplyDB

A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism

A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism

http://www.wikidata.org/entity/Q36491105

about

Alpha Klotho and phosphate homeostasis FGF23 and Phosphate Wasting Disorders Regulation and function of the FGF23/klotho endocrine pathways Fibroblast Growth Factor 23: A New Dimension to Diseases of Calcium-Phosphorus Metabolism Extracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to hypophosphatasia and X-linked hypophosphatemia Fibrous dysplasia and fibroblast growth factor-23 regulation Genetic disorders of phosphate regulation Klotho and phosphate are modulators of pathologic uremic cardiac remodeling.Novel bone endocrine networks integrating mineral and energy metabolism Increased bone volume and correction of HYP mouse hypophosphatemia in the Klotho/HYP mouse.Hypophosphatemic rickets: revealing novel control points for phosphate homeostasis.Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule.Circulating levels of soluble klotho and FGF23 in X-linked hypophosphatemia: circadian variance, effects of treatment, and relationship to parathyroid status Klotho deficiency causes vascular calcification in chronic kidney disease.Characterization of FN1-FGFR1 and novel FN1-FGF1 fusion genes in a large series of phosphaturic mesenchymal tumors.Recent advances in renal phosphate handling.Primary hyperparathyroidism: an overview.Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling.Regulation of phosphate transport by fibroblast growth factor 23 (FGF23): implications for disorders of phosphate metabolism.Hereditary hypophosphatemia in Norway: a retrospective population-based study of genotypes, phenotypes, and treatment complications.Discovery of alpha-Klotho unveiled new insights into calcium and phosphate homeostasis.Promoter methylation and age-related downregulation of Klotho in rhesus monkey Circulating αKlotho influences phosphate handling by controlling FGF23 production αKlotho: FGF23 coreceptor and FGF23-regulating hormone.Plasma soluble α-klotho protein levels in premature and term neonates: correlations with growth and metabolic parameters.Systemic Control of Bone Homeostasis by FGF23 Signaling.Insights from genetic disorders of phosphate homeostasis Identification of novel small molecules that elevate Klotho expression.Endocrine functions of bone in mineral metabolism regulation.The role of Klotho in energy metabolism.Expression of klotho mRNA and protein in rat brain parenchyma from early postnatal development into adulthood.Secreted klotho and chronic kidney disease The age-regulating protein klotho is vital to sustain retinal function.Familial tumoral calcinosis and the role of O-glycosylation in the maintenance of phosphate homeostasis.Klotho variants and chronic hemodialysis mortality Biochemical and functional characterization of the klotho-VS polymorphism implicated in aging and disease risk.Multilineage somatic activating mutations in HRAS and NRAS cause mosaic cutaneous and skeletal lesions, elevated FGF23 and hypophosphatemia.MicroRNA-339 and microRNA-556 regulate Klotho expression in vitro Disorders of phosphate homeostasis and tissue mineralisation.FGF23 and syndromes of abnormal renal phosphate handling

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A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism

http://www.wikidata.org/entity/Q36491105

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2008 nî lūn-bûn

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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A translocation causing increa ...... ickets and hyperparathyroidism

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A translocation causing increa ...... ickets and hyperparathyroidism

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A translocation causing increa ...... ickets and hyperparathyroidism

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A translocation causing increa ...... ickets and hyperparathyroidism

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A translocation causing increa ...... ickets and hyperparathyroidism

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Proceedings of the National Academy of Sciences of the United States of America

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A translocation causing increa ...... ickets and hyperparathyroidism

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Akihiro Imura

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Carol Nelson-Williams

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Felix Adler

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Junko Iijima

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Miguel Reyes-Mugica

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Peining Li

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Richard P Lifton

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Thomas O Carpenter

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Yo-Ichi Nabeshima

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P2860

Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

Refining the DFNB7-DFNB11 deafness locus using intragenic polymorphisms in a novel gene, TMEM2

New perspectives on the biology and treatment of X-linked hypophosphatemic rickets

Klotho converts canonical FGF receptor into a specific receptor for FGF23

GG: a domain involved in phage LTF apparatus and implicated in human MEB and non-syndromic hearing loss diseases

alpha-Klotho as a regulator of calcium homeostasis

Regulation of fibroblast growth factor-23 signaling by klotho

Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities

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3455-3460

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9

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105

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Catherine A. Brownstein

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2008-02-28T00:00:00Z

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5543362

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18308935

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hyperparathyroidism

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2265125

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