Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion. - Wikidata - awgldk - TriplyDB

Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion.

Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion.

http://www.wikidata.org/entity/Q36491754

about

PTP1B regulates Eph receptor function and trafficking The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function The novel adaptor protein Tks4 (SH3PXD2B) is required for functional podosome formation Regulation of Endothelial Adherens Junctions by Tyrosine Phosphorylation ER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interface Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling Spatiotemporal regulation of Src and its substrates at invadosomes Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation Src-mediated phosphorylation of mammalian Abp1 (DBNL) regulates podosome rosette formation in transformed fibroblasts Met receptor tyrosine kinase signals through a cortactin-Gab1 scaffold complex, to mediate invadopodia Actin-binding protein-1 interacts with WASp-interacting protein to regulate growth factor-induced dorsal ruffle formation.Integrins in cell migration Calpain-mediated proteolysis of paxillin negatively regulates focal adhesion dynamics and cell migration.Microtubule and cell contact dependency of ER-bound PTP1B localization in growth cones.A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion.LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis p53 in cell invasion, podosomes, and invadopodia Identification of novel inhibitors for a low molecular weight protein tyrosine phosphatase via virtual screening.Calpain- and talin-dependent control of microvascular pericyte contractility and cellular stiffness.Fibronectin induces epithelial-mesenchymal transition in human breast cancer MCF-7 cells via activation of calpain Amplification of the 20q chromosomal arm occurs early in tumorigenic transformation and may initiate cancer.Regulation of platelet-activating factor-mediated protein tyrosine phosphatase 1B activation by a Janus kinase 2/calpain pathway.Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasis.Impaired podosome formation and invasive migration of macrophages from patients with a PSTPIP1 mutation and PAPA syndrome Oncogenic Src requires a wild-type counterpart to regulate invadopodia maturation.PTP1B suppresses prolactin activation of Stat5 in breast cancer cells.Calpain 2 is required for glioblastoma cell invasion: regulation of matrix metalloproteinase 2.An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.Calpains as potential anti-cancer targets Cortactin: a multifunctional regulator of cellular invasiveness Podosomes and Invadopodia: Related structures with Common Protein Components that May Promote Breast Cancer Cellular Invasion.Identification of c-Src tyrosine kinase substrates in platelet-derived growth factor receptor signaling.PD-L1 expression is increased in a subset of basal type breast cancer cells.Fluid shear stress and sphingosine 1-phosphate activate calpain to promote membrane type 1 matrix metalloproteinase (MT1-MMP) membrane translocation and endothelial invasion into three-dimensional collagen matrices.Redox signaling at invasive microdomains in cancer cells.Calpain 2 is required for the invasion of glioblastoma cells in the zebrafish brain microenvironment.Calpain-mediated vimentin cleavage occurs upstream of MT1-MMP membrane translocation to facilitate endothelial sprout initiation.Calpain 2 regulates Akt-FoxO-p27(Kip1) protein signaling pathway in mammary carcinoma.Talin determines the nanoscale architecture of focal adhesions.

P2860

Q24313351-A0938D96-2C60-41FA-8884-35D1B6408578 Q24614572-1BED6234-4BFA-4DB6-BDF4-C0869F55B56E Q24647032-C1E9BF82-90FF-4170-8723-25D37DE68D57 Q26778080-88AFC4F1-BB7A-466A-91B9-C11957BE272B Q27301222-093F20D3-1FB8-4F76-86C0-A7C97442F264 Q28250146-31EC3E85-97A8-4F6F-8D66-2079C585FF12 Q28391160-5655C044-5ABC-46C2-86B7-B355058126CC Q28508669-A8368A05-C1DA-40ED-94CC-B8F7CE508282 Q28586428-141C90AE-7603-40E4-AC65-213E14ACF461 Q30010161-E051CC89-2B52-44E8-ACF0-69742E06BE35 Q30157056-0A5AF0DF-DBD5-44B3-A768-300C6C0FD769 Q30417364-60AD4E57-16E1-46DE-8DC0-5CD342CE9620 Q30427752-AAF45C33-8E60-4799-A46D-18BCFDD9B58D Q30486466-40170885-D726-4848-94B1-DB0CE98FA73C Q30582998-7E4A67D2-0757-40D1-BD7D-60B28B8611C6 Q30601534-2B27924A-301A-4C75-BFCF-48D838EA63DE Q30847518-CF01C6A0-7AF0-4EAD-9124-97C1EBBF28DB Q33358202-8C9D08C5-7B36-4575-951A-341C9BBF02D7 Q33600807-F8697D71-0433-4717-86DB-719FC3774751 Q33657916-E48C86A8-57CE-4D4D-BD3C-AABC59D7DC62 Q33684769-93A3E7D4-EEBE-4BCA-9B4F-CE4EFCC01993 Q33812864-8468621A-70B2-404D-A36D-19AAE37FF22F Q33884112-907482EE-1C4A-4DA2-BA8C-C2ED3CC800AF Q33994291-BD6C4D59-B822-4EB7-8C5E-E531AED276E8 Q34063462-54D539FB-CB20-4B61-9A17-DA321C482171 Q34273690-CFB69BAE-D842-45C8-B21D-AF6AA90952AB Q34358316-2267CFF1-24CE-4CB8-AD2F-5FB75830A061 Q34425717-C5232BF9-3A79-45F3-B26D-FC4A28BC6E97 Q34670759-3B7A0E6A-6603-4333-8E0F-F42BACB5C0D5 Q34793288-56EB7B2B-5E4F-4B98-8C73-8949720F3662 Q34891306-8678C27C-FB06-4391-AE34-5969005369A7 Q34897371-F2F1A56D-CBB4-4735-8545-E22B9F1B29E9 Q34994048-8A1657DA-F550-4809-A433-D6B02EDF0F0F Q35097436-942FCA0E-F685-41E5-BC97-DD9E0EC0FC99 Q35604895-E02A756C-AAAA-4189-87D8-BA305404B3EF Q35738096-C94FEF20-1DFA-47CD-B2FF-B296646AFB3A Q35742619-390A796D-03CA-4FB1-AE3D-66E8A07E407B Q35918764-56ABAFB0-74CE-4111-9153-B488CCDB8786 Q35939817-54906A6F-28AE-472C-9DD3-D5730E3DA5BE Q36055656-011151BE-0E0C-4342-9731-B50E6D2DE474

P2860

Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion.

http://www.wikidata.org/entity/Q36491754

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年学术文章

@wuu

2008年学术文章

@zh-cn

2008年学术文章

@zh-hans

2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Calpain 2 and PTP1B function i ...... d breast cancer cell invasion.

@ast

Calpain 2 and PTP1B function i ...... d breast cancer cell invasion.

@en

type

label

Calpain 2 and PTP1B function i ...... d breast cancer cell invasion.

@ast

Calpain 2 and PTP1B function i ...... d breast cancer cell invasion.

@en

prefLabel

Calpain 2 and PTP1B function i ...... d breast cancer cell invasion.

@ast

Calpain 2 and PTP1B function i ...... d breast cancer cell invasion.

@en

P1433

Q36491754-179605A8-021D-4487-B222-A9B95CD3ACDC

P1476

Q36491754-AECC7E2C-AABE-44A9-9AA9-5D746E7F5EB9

P2093

Q36491754-674C7804-ED46-45D4-9884-6527496987E5

Q36491754-6A10023B-173D-44C3-B9AA-1FC31F7AB0A9

Q36491754-AB0D8BD6-560A-4E7B-91A8-107DEB445CF8

Q36491754-E23822E5-6EDB-45EB-994F-46BC91D1AA19

Q36491754-E9EF71B5-8AA4-4B88-A8FC-7001BEEE65B7

P2860

Q36491754-022E099B-408F-415E-B0A9-DC6609CC340B

Q36491754-02EF771C-ACAA-403E-8FDB-5E5CA870F57B

Q36491754-0765C1BF-A5C6-4755-AB56-B4E9F9CA8C67

Q36491754-1390BA21-174D-43F2-9B01-97F2F0143901

Q36491754-1F300327-DBE3-4AFE-AB99-36BF1E205438

Q36491754-208BC3A2-383A-4EAD-8A5A-CB34BE820BCD

Q36491754-2165295B-01E3-40E9-B6DB-2E22C08C9E23

Q36491754-236433AF-6914-4790-B8EE-F1F049851CF6

Q36491754-288AE837-BA4A-4EFC-8C7F-5B60024CDB0E

Q36491754-2A97EF12-7374-41B5-B6D9-21D1E081912B

P304

Q36491754-6A8A2AA1-F3B0-4498-962E-1B9444172B64

P31

Q36491754-13598BC0-ACF2-41D2-BBF9-60E69240D8C2

P356

Q36491754-5C2CA352-A2A0-43B8-AE4B-51D1E841F714

P407

Q36491754-61055B56-760F-4B38-97D9-C7E44D34D8B3

P433

Q36491754-7EB2BECF-1288-44AF-BA36-1E3F703CB22D

P478

Q36491754-CA9F6771-079B-456F-BD1E-A730A88847E2

P50

Q36491754-56646C53-094F-42DE-B21B-C9803EF9840B

Q36491754-D6C59717-479C-4116-964F-59A8E99D1458

P577

Q36491754-20DE1D94-49B4-46EC-B515-44CA756B1BBA

P5875

Q36491754-B8A0B390-CE89-48FF-856E-FBA16D410E27

P698

Q36491754-7F3679BD-D2FF-4E18-A00F-DDB373449C9E

P932

Q36491754-FF939F05-F41B-4C5D-BA86-F92E0A33633A

P356

P1433

Journal of Cell Biology

P1476

Calpain 2 and PTP1B function i ...... nd breast cancer cell invasion

@en

P2093

Anna Huttenlocher

http://www.w3.org/2001/XMLSchema#string

Benjamin J Perrin

http://www.w3.org/2001/XMLSchema#string

Christa L Cortesio

http://www.w3.org/2001/XMLSchema#string

Sheng Zhang

http://www.w3.org/2001/XMLSchema#string

Zhong-Yin Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines

The role of protein-tyrosine phosphatase 1B in integrin signaling

RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

Inhibition of calpain stabilises podosomes and impairs dendritic cell motility

The matrix corroded: podosomes and invadopodia in extracellular matrix degradation

The molecular dynamics of osteoclast adhesions

Wiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cells

Cortactin is an essential regulator of matrix metalloproteinase secretion and extracellular matrix degradation in invadopodia

Regulation of cell migration by the calcium-dependent protease calpain.

P304

957-971

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1083/JCB.200708048

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

180

http://www.w3.org/2001/XMLSchema#string

P50

Nicholas O Burton

P577

2008-03-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5520473

http://www.w3.org/2001/XMLSchema#string

P698

18332219

http://www.w3.org/2001/XMLSchema#string

P932

2265405

http://www.w3.org/2001/XMLSchema#string