From bench to drug: human seizure modeling using Drosophila
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Exaggerated Nighttime Sleep and Defective Sleep Homeostasis in a Drosophila Knock-In Model of Human EpilepsyDistal spike initiation zone location estimation by morphological simulation of ionic current filtering demonstrated in a novel model of an identified Drosophila motoneuronCalcium Imaging of Neuronal Activity in Drosophila Can Identify Anticonvulsive CompoundsMutations of the Calcium Channel Gene cacophony Suppress Seizures in DrosophilaMutation of orthologous prickle genes causes a similar epilepsy syndrome in flies and humans.Increased persistent Na+ current contributes to seizure in the slamdance bang-sensitive Drosophila mutant.Secretory Carrier Membrane Protein (SCAMP) deficiency influences behavior of adult fliesFunctional Loss of Bmsei Causes Thermosensitive Epilepsy in Contractile Mutant Silkworm, Bombyx mori.An integrated micro- and macroarchitectural analysis of the Drosophila brain by computer-assisted serial section electron microscopy.Drosophila as a model for epilepsy: bss is a gain-of-function mutation in the para sodium channel gene that leads to seizures.Mutations in prickle orthologs cause seizures in flies, mice, and humans.Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.Regulation of membrane excitability: a convergence on voltage-gated sodium conductance.Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasisDrosophila Nipped-B Mutants Model Cornelia de Lange Syndrome in Growth and Behavior.A knock-in model of human epilepsy in Drosophila reveals a novel cellular mechanism associated with heat-induced seizure.A Drosophila model for Angelman syndrome.Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy.Drosophila melanogaster as a model organism of brain diseasesGenetic analysis of Drosophila melanogaster susceptibility to intestinal Vibrio cholerae infection.Computer modelling of epilepsyIon channels to inactivate neurons in DrosophilaSeizure and epilepsy: studies of seizure disorders in Drosophila.Potassium channels in Drosophila: historical breakthroughs, significance, and perspectives.Invertebrate and fungal model organisms: emerging platforms for drug discovery.Less is More: Reducing Tau Ameliorates Seizures in Epilepsy ModelsExtending julius seizure, a bang-sensitive gene, as a model for studying epileptogenesis: Cold shock, and a new insertional mutation.Identification of a novel synaptic protein, TMTC3, involved in periventricular nodular heterotopia with intellectual disability and epilepsy.julius seizure, a Drosophila Mutant, Defines a Neuronal Population Underlying Epileptogenesis.Slamdance: seizing a fly model for epilepsy.Defective cortex glia plasma membrane structure underlies light-induced epilepsy in mutants
P2860
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P2860
From bench to drug: human seizure modeling using Drosophila
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
From bench to drug: human seizure modeling using Drosophila
@ast
From bench to drug: human seizure modeling using Drosophila
@en
type
label
From bench to drug: human seizure modeling using Drosophila
@ast
From bench to drug: human seizure modeling using Drosophila
@en
prefLabel
From bench to drug: human seizure modeling using Drosophila
@ast
From bench to drug: human seizure modeling using Drosophila
@en
P2860
P1476
From bench to drug: human seizure modeling using Drosophila
@en
P2093
Mark A Tanouye
P2860
P304
P356
10.1016/J.PNEUROBIO.2007.10.006
P577
2007-10-26T00:00:00Z