IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation
about
Ovol2 suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing c-Myc and Notch1poky/chuk/ikk1 is required for differentiation of the zebrafish embryonic epidermis.IKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancerHINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cellsPathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiationTGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisTGFbeta in CancerTranscriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cellsPalmitoylation regulates epidermal homeostasis and hair follicle differentiationDeciphering the role of nuclear and cytoplasmic IKKα in skin cancerBMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production.Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.Bronchial epithelial cells are rendered insensitive to glucocorticoid transactivation by transforming growth factor-β1.The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.Ketamine exposure in early development impairs specification of the primary germ cell layers.Reduction of IKKalpha expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesisTGFβ1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factorsOxidative stress increases phosphorylation of IkappaB kinase-alpha by enhancing NF-kappaB-inducing kinase after transient focal cerebral ischemia.Evolution of the TGF-β signaling pathway and its potential role in the ctenophore, Mnemiopsis leidyi.Inhibitor of NF-kappa B kinases alpha and beta are both essential for high mobility group box 1-mediated chemotaxis [corrected]The IκB kinase complex is required for plexin-B-mediated activation of RhoAInhibition of choriodecidual cytokine production and inflammatory gene expression by selective I-kappaB kinase (IKK) inhibitors.Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotypeInduction of ΔNp63 by the newly identified keratinocyte-specific transforming growth factor β Signaling Pathway with Smad2 and IκB Kinase α in squamous cell carcinoma.An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis.Six1 overexpression at early stages of HPV16-mediated transformation of human keratinocytes promotes differentiation resistance and EMT.dickkopf-3-related gene regulates the expression of zebrafish myf5 gene through phosphorylated p38a-dependent Smad4 activity.IKKα/CHUK regulates extracellular matrix remodeling independent of its kinase activity to facilitate articular chondrocyte differentiation.Alternative nuclear functions for NF-κB family membersIKKα represses a network of inflammation and proliferation pathways and elevates c-Myc antagonists and differentiation in a dose-dependent manner in the skinIKK biology.IκB kinase alpha and cancerToward an orofacial gene regulatory network.The harmonies played by TGF-β in stem cell biology.The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.The tumor suppressor activity of IKKalpha in stratified epithelia is exerted in part via the TGF-beta antiproliferative pathwayIRF6 in development and disease: a mediator of quiescence and differentiation.Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma.FGFR2IIIb-MAPK Activity Is Required for Epithelial Cell Fate Decision in the Lower Müllerian Duct
P2860
Q24336924-EBC32A90-BA58-4DC8-AE0C-50CD272C266DQ24630517-CCA2E748-0737-45ED-BA22-EAB61198D39CQ24642963-4B367907-5400-4922-B921-0F76284B939BQ24645174-36E8A597-FC4A-4EC0-9094-3945D3E6267FQ26777901-F71F5EBD-8F67-4EE1-BC85-7AF76586C878Q28083107-9D567FE8-0E4A-48A4-B79A-CECDDEA4BB48Q28288866-1365C810-9846-411C-BC50-56D174E8F754Q28586650-4FA3F7B3-02B6-4C5B-9149-264C7C417EF1Q28594751-DDE524AE-FDB9-4D3F-ACAE-9A7AA8A222CAQ28828173-6013E132-1572-4F4C-8335-8C1A4B036DABQ31047574-8C54AD04-165C-4EBF-8056-A807138E0385Q31814759-8B703A72-8303-40E0-802B-680A0A9DEB67Q33358710-CA6ED1FE-5AF6-4AC9-AEFD-86C124A9BD0DQ33613763-C5C83764-437F-4C75-8EF4-9E3F76D969B1Q33686963-F4DEAB95-EB32-49F9-AD6D-F4F2491914AFQ33715726-1986B6ED-7DE4-4411-90B7-0FA7D0D3E0D5Q33816459-47293122-5593-41C0-AFDD-5937BF12F9D4Q33827621-A24D9B80-8E7C-4635-AB9E-EC009ACB8B64Q33926105-3A391900-FB40-4992-882A-3B5B22D0BC84Q34023296-64547165-5643-4F58-8FBE-664FAE8431C2Q34043446-96C1D8D0-0EA2-4CEB-B4BA-1E1F422289F6Q34066731-CC9FEF71-3CA5-4180-991F-7E9BE6E1D700Q34116837-BFA05C92-9617-4245-9EC7-C9F9515E57C9Q34181612-0622E932-AB19-41D8-A92E-0942F9FC6249Q34411687-E53CE9F2-A8C5-49D4-BA87-986315E17796Q34467651-AC420CF4-C52B-475E-A3B0-9C0396B0D531Q34657109-AB12AEE5-1A4F-4A6A-92C9-3C987615E684Q34675912-3B8F0E7E-9C90-4FAC-8BE4-07351566EB8CQ34984184-DFAA4DBE-4DC4-4240-ACA9-79E8313E9C03Q35263997-19FCE86E-423E-4896-96B9-3627E143FE81Q35546349-1EE62047-A56F-4718-8410-C4DE9A5CEAD0Q35848596-557D8A30-9F25-4473-A7E9-79B100EA6B72Q35872007-08D59824-B2ED-4017-B6DB-B1A95092F2D4Q36586034-0CF7E30D-5AC2-4310-96AD-4C6EEB0C51BEQ36730830-E785A488-224F-44E4-AB37-E151F4EE4769Q36829459-E1606AFE-C8F7-44BD-AF17-C13991C1C26EQ36964339-AB1AB5F4-8909-4710-9608-EB655F9957B3Q36968117-EC186CC2-9905-4621-B40B-36E151D97825Q37022229-BF6DB667-AD52-4CFA-A53A-4535B973AD62Q37050103-091EBBB0-511C-4B1F-B65C-0E33083D2ABE
P2860
IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
IKKalpha is a critical coregul ...... s keratinocyte differentiation
@ast
IKKalpha is a critical coregul ...... s keratinocyte differentiation
@en
type
label
IKKalpha is a critical coregul ...... s keratinocyte differentiation
@ast
IKKalpha is a critical coregul ...... s keratinocyte differentiation
@en
prefLabel
IKKalpha is a critical coregul ...... s keratinocyte differentiation
@ast
IKKalpha is a critical coregul ...... s keratinocyte differentiation
@en
P2093
P2860
P356
P1476
IKKalpha is a critical coregul ...... s keratinocyte differentiation
@en
P2093
Alok K Sil
Gangwen Han
Olexandr Korchynskyi
Pascal Descargues
Philip Owens
Xiao-Jing Wang
P2860
P304
P356
10.1073/PNAS.0712044105
P407
P577
2008-02-11T00:00:00Z