The antinociceptive effects of nicotinic receptors α7-positive allosteric modulators in murine acute and tonic pain models.
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Role of α7 nicotinic receptor in the immune system and intracellular signaling pathwaysThe minimal pharmacophore for silent agonism of the α7 nicotinic acetylcholine receptor.A type-II positive allosteric modulator of α7 nAChRs reduces brain injury and improves neurological function after focal cerebral ischemia in rats.High therapeutic potential of positive allosteric modulation of α7 nAChRs in a rat model of traumatic brain injury: proof-of-conceptEffects of nicotinic acetylcholine receptor agonists in assays of acute pain-stimulated and pain-depressed behaviors in rats.In silico target fishing and pharmacological profiling for the isoquinoline alkaloids of Macleaya cordata (Bo Luo Hui)Critical Molecular Determinants of α7 Nicotinic Acetylcholine Receptor Allosteric Activation: SEPARATION OF DIRECT ALLOSTERIC ACTIVATION AND POSITIVE ALLOSTERIC MODULATION.The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors in MiceA positive allosteric modulator of α7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia.Effects of neuronal nicotinic acetylcholine receptor allosteric modulators in animal behavior studies.The activity of GAT107, an allosteric activator and positive modulator of α7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface.The therapeutic promise of positive allosteric modulation of nicotinic receptors.Nicotinic Modulation of Descending Pain Control Circuitry.1,3-diphenylpropan-1-ones as allosteric modulators of α7 nACh receptors with analgesic and antioxidant properties.Effects of nicotine in combination with drugs described as positive allosteric nicotinic acetylcholine receptor modulators in vitro: discriminative stimulus and hypothermic effects in mice.The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain.Sex Differences and Drug Dose Influence the Role of the α7 Nicotinic Acetylcholine Receptor in the Mouse Dextran Sodium Sulfate-Induced Colitis Model.The interaction between alpha 7 nicotinic acetylcholine receptor and nuclear peroxisome proliferator-activated receptor-α represents a new antinociceptive signaling pathway in mice.New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs.The current agonists and positive allosteric modulators of α7 nAChR for CNS indications in clinical trials.Nicotinic acetylcholine receptors in neuropathic and inflammatory pain.Boosting Endogenous Resistance of Brain to Ischemia.Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal.
P2860
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P2860
The antinociceptive effects of nicotinic receptors α7-positive allosteric modulators in murine acute and tonic pain models.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The antinociceptive effects of ...... e acute and tonic pain models.
@ast
The antinociceptive effects of ...... e acute and tonic pain models.
@en
type
label
The antinociceptive effects of ...... e acute and tonic pain models.
@ast
The antinociceptive effects of ...... e acute and tonic pain models.
@en
prefLabel
The antinociceptive effects of ...... e acute and tonic pain models.
@ast
The antinociceptive effects of ...... e acute and tonic pain models.
@en
P2093
P2860
P356
P1476
The antinociceptive effects of ...... e acute and tonic pain models.
@en
P2093
F Ivy Carroll
Kelen Freitas
M Imad Damaj
P2860
P304
P356
10.1124/JPET.112.197871
P407
P577
2012-10-31T00:00:00Z