SCG10 is a JNK target in the axonal degeneration pathway. - Wikidata - awgldk - TriplyDB

SCG10 is a JNK target in the axonal degeneration pathway.

SCG10 is a JNK target in the axonal degeneration pathway.

http://www.wikidata.org/entity/Q36504487

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MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling JNK Signaling: Regulation and Functions Based on Complex Protein-Protein Partnerships Axonal transport: cargo-specific mechanisms of motility and regulation The DLK signalling pathway--a double-edged sword in neural development and regeneration Death Receptor 6 Promotes Wallerian Degeneration in Peripheral Axons.A role for the p75 neurotrophin receptor in axonal degeneration and apoptosis induced by oxidative stress Axon injury and regeneration in the adult Drosophila Identification of palmitoyltransferase and thioesterase enzymes that control the subcellular localization of axon survival factor nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2)Preserve and protect: maintaining axons within functional circuits.Spy1 Protein Mediates Phosphorylation and Degradation of SCG10 Protein in Axonal Degeneration.Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon Regeneration dMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation.ROS regulation of axonal mitochondrial transport is mediated by Ca2+ and JNK in Drosophila Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies.KIF5C S176 Phosphorylation Regulates Microtubule Binding and Transport Efficiency in Mammalian Neurons.Axonal trafficking of NMNAT2 and its roles in axon growth and survival in vivo.MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.Fetal cannabinoid receptors and the "dis-joint-ed" brain.Miswiring the brain: Δ9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway.Nuclear and cytosolic JNK signalling in neurons.Wallerian degeneration: an emerging axon death pathway linking injury and disease.Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.Mechanisms of distal axonal degeneration in peripheral neuropathies.Stress Increases Peripheral Axon Growth and Regeneration through Glucocorticoid Receptor-Dependent Transcriptional Programs.Molecular mechanisms in the initiation phase of Wallerian degeneration.Axon degeneration: context defines distinct pathways.Roles of palmitoylation in axon growth, degeneration and regeneration.Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma.Kif1B Interacts with KBP to Promote Axon Elongation by Localizing a Microtubule Regulator to Growth Cones.Proximity of SCG10 and prion protein in membrane rafts.JUN is important for ocular hypertension-induced retinal ganglion cell degeneration.The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction.GSK3B-mediated phosphorylation of MCL1 regulates axonal autophagy to promote Wallerian degeneration.Can a death signal half-life be used to sense the distance to a lesion site in axons?Dynamic regulation of SCG10 in regenerating axons after injury.Modulation of nuclear REST by alternative splicing: a potential therapeutic target for Huntington's disease.Sustained GSK3 activity markedly facilitates nerve regeneration.A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria.Stress-Activated Protein Kinases in Spinal Cord Injury: Focus on Roles of p38.TRPV1 Agonist, Capsaicin, Induces Axon Outgrowth after Injury via Ca2+/PKA Signaling.

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P2860

SCG10 is a JNK target in the axonal degeneration pathway.

http://www.wikidata.org/entity/Q36504487

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name

SCG10 is a JNK target in the axonal degeneration pathway.

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SCG10 is a JNK target in the axonal degeneration pathway.

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type

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SCG10 is a JNK target in the axonal degeneration pathway.

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SCG10 is a JNK target in the axonal degeneration pathway.

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prefLabel

SCG10 is a JNK target in the axonal degeneration pathway.

@ast

SCG10 is a JNK target in the axonal degeneration pathway.

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P1476

SCG10 is a JNK target in the axonal degeneration pathway

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P2093

Bradley R Miller

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Elisabetta Babetto

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Emilie V Russler

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Shehzad Qayum

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Valeria Cavalli

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Yo Sasaki

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Yongcheol Cho

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P2860

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves

Identification of in vitro phosphorylation sites in the growth cone protein SCG10. Effect Of phosphorylation site mutants on microtubule-destabilizing activity

Role of axonal transport in neurodegenerative diseases

Bcl-XL and Bcl-2 repress a common pathway of cell death

JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length

Stimulation of nicotinamide adenine dinucleotide biosynthetic pathways delays axonal degeneration after axotomy

Axon degeneration: Molecular mechanisms of a self-destruction pathway

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

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52

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109

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Jeffrey Milbrandt

Aaron DiAntonio

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2012-11-27T00:00:00Z

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23188802

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3535671

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