Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein. - Wikidata - awgldk - TriplyDB

Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein.

Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein.

http://www.wikidata.org/entity/Q36509133

about

Archaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and Function The minichromosome maintenance replicative helicase MCM ring hexamerization is a prerequisite for DNA-binding.Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicase A conserved MCM single-stranded DNA binding element is essential for replication initiation Insights into the MCM functional mechanism: lessons learned from the archaeal MCM complex.Mutations in subdomain B of the minichromosome maintenance (MCM) helicase affect DNA binding and modulate conformational transitions The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines.Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication.Different residues on the surface of the Methanothermobacter thermautotrophicus MCM helicase interact with single- and double-stranded DNA.Characterization of the MCM homohexamer from the thermoacidophilic euryarchaeon Picrophilus torridus.Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding.Analysis of the crystal structure of an active MCM hexamer Thermococcus kodakarensis encodes three MCM homologs but only one is essential.Intersubunit allosteric communication mediated by a conserved loop in the MCM helicase The Mcm complex: unwinding the mechanism of a replicative helicase.Structural biology of MCM helicases.G364R mutation of MCM4 detected in human skin cancer cells affects DNA helicase activity of MCM4/6/7 complex.Mechanisms and regulation of DNA replication initiation in eukaryotes.Mutational analysis of conserved aspartic acid residues in the Methanothermobacter thermautotrophicus MCM helicase.Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis.The solution structure of full-length dodecameric MCM by SANS and molecular modeling

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P2860

Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein.

http://www.wikidata.org/entity/Q36509133

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Coupling of DNA binding and he ...... erved loop in the MCM protein.

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Coupling of DNA binding and he ...... erved loop in the MCM protein.

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Coupling of DNA binding and he ...... erved loop in the MCM protein.

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Coupling of DNA binding and he ...... erved loop in the MCM protein.

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Coupling of DNA binding and he ...... erved loop in the MCM protein.

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Coupling of DNA binding and he ...... erved loop in the MCM protein.

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Nucleic Acids Research

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Coupling of DNA binding and he ...... erved loop in the MCM protein.

@en

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Eugene Melamud

http://www.w3.org/2001/XMLSchema#string

Frederick P Schwarz

http://www.w3.org/2001/XMLSchema#string

Mimi Han

http://www.w3.org/2001/XMLSchema#string

Nozomi Sakakibara

http://www.w3.org/2001/XMLSchema#string

Rajesh Kasiviswanathan

http://www.w3.org/2001/XMLSchema#string

Zvi Kelman

http://www.w3.org/2001/XMLSchema#string

P2860

mcm5/cdc46-bob1 bypasses the requirement for the S phase activator Cdc7p

Interactions between the archaeal Cdc6 and MCM proteins modulate their biochemical properties.

The structure and function of MCM from archaeal M. Thermoautotrophicum

Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex.

Hexameric ring structure of the full-length archaeal MCM protein complex.

The hexameric eukaryotic MCM helicase: building symmetry from nonidentical parts.

Minichromosome maintenance helicase activity is controlled by N- and C-terminal motifs and requires the ATPase domain helix-2 insert.

GINS, a central nexus in the archaeal DNA replication fork.

Eukaryotic MCM proteins: beyond replication initiation.

Archaeal DNA replication and repair.

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1309-1320

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scholarly article

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10.1093/NAR/GKM1160

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4

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36

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2008-01-09T00:00:00Z

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5665430

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18184696

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2275104

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