Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development - Wikidata - awgldk - TriplyDB

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

http://www.wikidata.org/entity/Q36509989

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The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma The role of the ubiquitin proteasome system in cerebellar development and medulloblastoma Not so Fast: Co-Requirements for Sonic Hedgehog Induced Brain Tumorigenesis Where hearing starts: the development of the mammalian cochlea Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity Control of the Normal and Pathological Development of Neural Stem and Progenitor Cells by the PC3/Tis21/Btg2 and Btg1 Genes Cerebellum development and medulloblastoma Development and cancer of the cerebellum Signaling and Transcription Factors during Inner Ear Development: The Generation of Hair Cells and Otic Neurons.The Role of Atonal Factors in Mechanosensory Cell Specification and Function Atoh1 expression and function during auditory hair cell regeneration in post-hatch chickens.Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: function, regulation, and context dependency.Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion.Evolutionary changes in transcription factor coding sequence quantitatively alter sensory organ development and function The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development.Cooperative activity of noggin and gremlin 1 in axial skeleton development.Identification of small molecule activators of BMP signaling Deregulated proliferation and differentiation in brain tumors.WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation.In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.High expression of BMP pathway genes distinguishes a subset of atypical teratoid/rhabdoid tumors associated with shorter survival.Expression of bone morphogenetic protein-2 and -7 in urinary bladder cancer predicts time to tumor recurrence.Canonical BMP7 activity is required for the generation of discrete neuronal populations in the dorsal spinal cord.ASC deficiency suppresses proliferation and prevents medulloblastoma incidence Bone morphogenetic protein modulator BMPER is highly expressed in malignant tumors and controls invasive cell behavior.Epigenetic regulation of cancer stem cells in liver cancer: current concepts and clinical implications.Candidate pathways for promoting differentiation or quiescence of oligodendrocyte progenitor-like cells in glioma.Medulloblastoma or not? Crucial role in tumorigenesis of the timing of migration of cerebellar granule precursor cells, regulated by Nos2 and Tis21 Unique genetic and epigenetic mechanisms driving paediatric diffuse high-grade glioma.Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells.Pediatric gliomas as neurodevelopmental disorders The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea.Consensus Paper: Cerebellar Development.Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma.Distinct roles for fibroblast growth factor signaling in cerebellar development and medulloblastoma.

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P2860

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

http://www.wikidata.org/entity/Q36509989

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Post-transcriptional down-regu ...... es medulloblastoma development

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Post-transcriptional down-regu ...... es medulloblastoma development

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Post-transcriptional down-regu ...... es medulloblastoma development

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Post-transcriptional down-regu ...... es medulloblastoma development

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Post-transcriptional down-regu ...... es medulloblastoma development

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Post-transcriptional down-regu ...... es medulloblastoma development

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Frederique Zindy

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Haotian Zhao

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Jee-Hae Kim

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Olivier Ayrault

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P2860

Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

Medulloblastoma: developmental mechanisms out of control

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway

Mouse Zic1 is involved in cerebellar development

Signaling by bone morphogenetic proteins and Smad1 modulates the postnatal differentiation of cerebellar cells

Pax6 regulates granule cell polarization during parallel fiber formation in the developing cerebellum

NeuroD is required for differentiation of the granule cells in the cerebellum and hippocampus

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development

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6

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22

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Martine F Roussel

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medulloblastoma

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2275424

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