Pak2 kinase restrains mast cell FcεRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity.
about
Mast cell activation: a complex interplay of positive and negative signaling pathwaysp21-Activated kinase (PAK) regulates cytoskeletal reorganization and directional migration in human neutrophilsp21-Activated Kinase 2 Regulates Endothelial Development and Function through the Bmk1/Erk5 PathwayPak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiationPAK signalling during the development and progression of cancerGroup I PAK inhibitor IPA-3 induces cell death and affects cell adhesivity to fibronectin in human hematopoietic cellsPak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization.Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation.Dynamic association of the PI3P-interacting Mon1-Ccz1 GEF with vacuoles is controlled through its phosphorylation by the type 1 casein kinase Yck3.Potential compensation among group I PAK members in hindlimb ischemia and wound healing.Control of vascular permeability by atrial natriuretic peptide via a GEF-H1-dependent mechanism.Role of p21-activated kinases in cardiovascular development and function.Hyperoside regulates the level of thymic stromal lymphopoietin through intracellular calcium signalling.Differential role for PAK1 and PAK4 during the invadopodia lifecycle.Modulation of store-operated calcium entry and nascent adhesion by p21-activated kinase 1.Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer
P2860
Q26824984-4EBE2307-13EB-45D8-898A-AFA84F093BB5Q27308144-172275E8-7843-4BB4-B173-4690DE1506B6Q27320786-01A2D6ED-ECA7-42D9-9313-CDA31853620AQ28255514-75DFFA15-486D-41B4-9FA6-73FE471632D4Q28307460-9E36ECCE-D6C8-4E9B-9D65-15D82369980FQ28541395-1CE6D95F-3E74-44F7-962E-1AC3FAFE0FB7Q33421593-0AF7842E-1889-4390-8C6B-BF90FCCC7606Q33597132-D267502D-B105-416E-96A9-5FBCEBAF2F65Q33604383-21B5FE19-DAF4-4FAC-B1BE-F4EE82143092Q34473172-E99E175C-5032-4126-AEC6-1392B71EB5FFQ37596383-A1D05BC7-697F-469E-83B3-5F53F9A11D38Q38103812-1980482A-544F-4B67-99B0-09DFABDE6E21Q39043154-97F2F720-AF78-498B-849A-64BD682BBD1AQ39181978-5813F04E-2F56-4F9C-92C5-CFDFA7C84EECQ54108553-EB6CCDF2-F41D-4EB2-9CF2-F7B5C21D1F20Q57980063-D661C1E2-A614-485D-9C32-E0026C2930D6
P2860
Pak2 kinase restrains mast cell FcεRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Pak2 kinase restrains mast cel ...... xchange factor (GEF) activity.
@ast
Pak2 kinase restrains mast cel ...... xchange factor (GEF) activity.
@en
type
label
Pak2 kinase restrains mast cel ...... xchange factor (GEF) activity.
@ast
Pak2 kinase restrains mast cel ...... xchange factor (GEF) activity.
@en
prefLabel
Pak2 kinase restrains mast cel ...... xchange factor (GEF) activity.
@ast
Pak2 kinase restrains mast cel ...... xchange factor (GEF) activity.
@en
P2093
P2860
P356
P1476
Pak2 kinase restrains mast cel ...... xchange factor (GEF) activity.
@en
P2093
Hoi Yee Chow
Jonathan Chernoff
Maria Radu
Rachelle Kosoff
P2860
P304
P356
10.1074/JBC.M112.422295
P407
P577
2012-11-30T00:00:00Z